Detection of Lethal SNP (A781G) in Growth Hormone (GH) gene of Indian Sheep

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dc.contributor.authorSeevagan, M.
dc.contributor.authorJeichitra, V.
dc.contributor.authorRajendran, R.
dc.contributor.authorTirumurugaan, K.G.
dc.contributor.authorTANUVAS
dc.date.accessioned2017-03-24T05:24:25Z
dc.date.available2017-03-24T05:24:25Z
dc.date.issued2015
dc.description.abstractThe polymorphism of A781G locus of the growth hormone (GH) gene was analyzed in 112 Vembur sheep. HaeIII – RFLP of the GH gene (422 bp) revealed the existence of two genotypes viz., AA (366 and 56 bp) and AB (422, 366 and 56 bp), and two alleles viz., A and B. Genotypic frequencies for AA and AB were 0.43 and 0.57, and allelic frequencies were 0.71 and 0.29 for A and B respectively. BB genotype was absent. Highly significant Chi-square value (P < 0.001) showed that the population is not under Hardy–Weinberg equilibrium at the A781G locus. This indicates that molecular markers associated with embryonic survival are to be explored for their use in MAS in Vembur population.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810005838
dc.keywordsVeterinary Science, Animal Genetic Resources, Vembur Sheep, Lethal genotype, Growth hormone, PCR-RFLP, Polymorphismen_US
dc.language.isoen_USen_US
dc.pages3en_US
dc.publisherElsevieren_US
dc.subjectAnimal Genetic Resourcesen_US
dc.subjectAnimal Genetics and Breedingen_US
dc.titleDetection of Lethal SNP (A781G) in Growth Hormone (GH) gene of Indian Sheepen_US
dc.title.alternativeTNV_SRR_126_2015_13-15en_US
dc.typeArticleen_US
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