Prevalence, clinico-pathology and therapeutic studies of Coccidiosis in broiler birds with special reference to herbal therapy
| dc.contributor.advisor | Shukla, S.K. | |
| dc.contributor.author | Sudhanshu Shekhar | |
| dc.date.accessioned | 2017-07-13T10:16:23Z | |
| dc.date.available | 2017-07-13T10:16:23Z | |
| dc.date.issued | 2016-08 | |
| dc.description.abstract | The present work was conducted to study the prevalence of coccidiosis in commercial broiler and layer farms located in the district Udham Singh Nagar of Uttarakhand, India from January 2015 to December 2015. Anticoccidial activity of some herbal extracts was evaluated in experimentally induced coccidiosis in broilers and their efficacy compared with amprolium. The prevalence of disease was higher in broiler farms (59.09%) of small flock strength (76.92%) in 3-6 week age group (92.30%). Prevalence was also high in monsoon season (55.0%). ITS-1 based nested PCR identified six Eimeria species, i.e. E. tenella, E. necatrix, E. mitis, E. acervulina, E. praecox and E. brunette, and overall prevalence of these species were 95, 65, 45, 45, 35 and 20%, respectively. The physiochemical and phytochemical analysis of aqueous and methanolic extracts of Musa paradisiaca, Ageratum conyzoides and Melia azedarach revealed that these plant were rich in crude protein, crude fiber, NFE, organic matter, minerals, alkaloids, sterols, glycosides, phenols, protein, tannins, flavanoid, terpenoids, etc. The total phenol and total flavanoid, antioxidant activity were higher and IC50 value was lower in methanolic extract as compared to aqueous extract residues of these plant. The GC-MS analysis of crude methanolic extract of these plants showed presence of several biological active compounds. Preliminary acute toxicity study of methanolic and aqueous extracts of these plant showed that all the extract residues were safe and did not produce any toxic effect even at higher dose (5000 mg/kg b.wt.) in broilers. In vivo anticoccidial activity of aqueous and methanolic extracts of these plants was assessed either alone or in combination and compared the activity with the standard anticoccidial drugs amprolium. For the purpose, 300 day old broiler chicks were randomly divided in 20 groups of 15 birds each. The efficacy of these extracts was evaluated on the basis of parasitological, haematological, biochemical, immunological, serum mineral level, oxidative stress and histopatholgical studies. It was concluded from the study that methanolic extract of triherb complex (1:1:1) and methanolic extract of A. conyzoides @ 1000 mg/kg b.wt. for 7 day revealed better anticoccidial activity against E. tenella infection in broiler which was comparable with amprolium. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810025165 | |
| dc.keywords | disease prevalence, clinical aspects, therapy, coccidiosis, broilers, birds herbal drugs, aviaries, medicinal plants | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand) | en_US |
| dc.research.problem | Aviaries | en_US |
| dc.sub | Veterinary Medicine | en_US |
| dc.subject | null | en_US |
| dc.theme | Veterinary Pharmacology & Toxicology | en_US |
| dc.these.type | Ph.D | en_US |
| dc.title | Prevalence, clinico-pathology and therapeutic studies of Coccidiosis in broiler birds with special reference to herbal therapy | en_US |
| dc.type | Thesis | en_US |