Preparation of autogenous vaccine against multi drug resistant Klebsiella pneumoniae outbreak in a rabbit farm
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Date
2015-02
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Abstract
Ailing and dead rabbits, brought to the Department of Veterinary Microbiology, VCRI, Namakkal, with a history
of anorexia, severe respiratory distress, mucus discharge from the nostril, mild enteritis and recumbency few hours
before death, were used for the study. Relevant samples were collected and subjected to cultural examination on
nutrient and MacConkey media. Klebsiella pneumoniae was isolated in pure culture and identified by morphological,
staining, cultural and biochemical characters. Antibiotic sensitivity test showed multi-drug resistance. Inactivated
vaccine was prepared by mixing mineral oil, surfactants and Klebsiella pneumoniae culture in the ratio of 6:1:3.
Sterility and safety checking tests were carried out and the vaccine was administered to the rabbits. It produced
noticeable protection against the disease.
Description
TNV_IJAS_2015_85(2)126-128
Keywords
Veterinary Science