CLINICO–DIAGNOSTIC AND THERAPEUTIC STUDIES ON DIARRHOEA IN BUFFALO CALVES WITH BACTERIAL INVOLVEMENT

dc.contributor.advisorSuresh, K(MAJOR)
dc.contributor.advisorLakshmi Rani, N
dc.contributor.advisorHari Krishna, N.V.V
dc.contributor.authorSURENDRA, BADVEL
dc.date.accessioned2023-03-26T04:17:11Z
dc.date.available2023-03-26T04:17:11Z
dc.date.issued2022-05
dc.descriptionTHESESen_US
dc.description.abstractThe present study was undertaken to record the occurrence, clinical signs, haemato-biochemical findings, antibiotic sensitivity pattern and to assess the therapeutic regimen in diarrhoeic buffalo calves with bacterial involvement presented to the large animal medicine ward, in dairy farms located in and around Gannavaram, Krishna district. Out of 226 calves presented, 81 were affected with diarrhea of which in 42 calves diarrhoea was due to bacterial involvement, while in 37 diarrhoea was due to parasitic infestation Viz., Toxocara spp. in 30 (13.27%) and Eimeria spp. in 7 calves (3.09%) and in 2 calves diarrhoea was tentatively due to rota viral infection (0.88%). The overall occurrence of diarrhoea in buffalo calves with bacterial involvement was 18.58 per cent (42/226) with respect to cases presented and it was 51.68 per cent with respect to 81 diarrhoeic calves screened (42/81). Occurrence of diarrhoea in buffalo calves with bacterial involvement was highest in calves below 10 days age (64.29 %) followed by 10-20 days age (26.19 %) and lowest in calves above 21-30 days of age (9.52 %). Highest occurrence was recorded in male calves (54.76%) when compared to female calves (45.24%). The clinical signs exhibited by diarrhoeic buffalo calves with bacterial involvement were diarrhoea, loss of appetite, dehydration, depression, congested conjunctival mucous membrane, increased heart rate, increased respiratory rate, rise in temperature, poor suckling reflex and soiling of perineum and tail with faeces. Clinical observations in diarrhoeic buffalo calves with bacterial involvement revealed non-significant increase in temperature, significant increase in skin elasticity time, capillary refill time and eye ball recession depth. Faecal sample of diarrhoeic buffalo calves with bacterial involvement was subjected for isolation, identification and cultural examination. Bacterial isolates up on cultural examination and biochemical tests revealed that highest per cent isolated was Escherichia coli alone (59.52%), followed by mixed infection with Escherichia coli +Klebsiella spp. (14.30%), Klebsiella spp. alone (9.52%), Escherichia spp. + Pseudomonas spp. (7.14%), Salmonella spp. and Pseudomonas spp. (4.76% each). Antibiotic sensitivity test of E. coli isolates showed highest sensitivity to ceftriaxone, amoxicillin clavulanic acid, amikacin and ciprofloxacin in the descending order. ABST of Klebsiella spp. isolates showed highest sensitivity to ceftriaxone and ciprofloxacin. Pseudomonas spp. isolates were sensitive to ciprofloxacin and Salmonella spp. isolates showed highest sensitivity to amikacin, ceftriaxone and ciprofloxacin. Haemato-biochemical findings revealed significant increase in haemoglobin, PCV, TLC, TEC, DLC, neutrophilia and significant lymphocytopenia. Significant increase in serum total protein and potassium while significant decrease in glucose, sodium and chloride levels were recorded. Therapeutic trial was conducted in 24 diarrhoeic buffalo calves affected with colibacillosis by dividing them in 3 groups using three different antibiotic regimens Viz., parenteral amoxicillin sulbactam, ceftriaxone tazobactam and amikacin along with rehydration and supportive therapy in common for all the groups and all the antibiotics were effective in the treatment of colibacillosis while ceftriaxone tazobactam was found to be more efficacious followed by amoxicillin sulbactam and amikacin.en_US
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810195798
dc.keywordsDIARRHOEA; BUFFALO CALVES; BACTERIAL INVOLVEMENT; CLINICO–DIAGNOSTIC; THERAPEUTIC STUDIESen_US
dc.language.isoEnglishen_US
dc.pages153en_US
dc.publisherSRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIAen_US
dc.subVeterinary Medicineen_US
dc.themeCLINICO–DIAGNOSTIC AND THERAPEUTIC STUDIES ON DIARRHOEA IN BUFFALO CALVES WITH BACTERIAL INVOLVEMENTen_US
dc.these.typeM.V.Sc.en_US
dc.titleCLINICO–DIAGNOSTIC AND THERAPEUTIC STUDIES ON DIARRHOEA IN BUFFALO CALVES WITH BACTERIAL INVOLVEMENTen_US
dc.typeThesisen_US
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