IDENTIFICATION OF METASTATIC POTENTIAL OF MAMMARY TUMOUR IN DOGS
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Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
TANUVAS
Abstract
The current research work was programmed with the objective of studying
the diagnostic significance of expression of metastatic markers E-cadherin, MMP-
2 and C-erbB2 in canine mammary tumours. The study showed occurrence of 229
neoplastic conditions of which 80 dogs (75 females and 5 males) had mammary
tumours, with a population incidence of 0.11 per cent. The per cent incidence of
mammary tumour among the tumour cases was 34.94. The highest incidence of
mammary tumour was observed in the age range 8 to <12 years (50%). The
tumour occurrence was high in pure breeds of dogs (73.75%) in which Spitz
(32.20%) was predominantly affected. Intact females (92%) were mostly affected
compared to the spayed dogs. The inguinal (42.31% in females; 60% in males)
and caudal abdominal glands (40.38% in females; 40% in males) were
predominantly affected. Anaemia, leukocytosis with neutrophilia, increased total
protein, ALP and calcium and decreased creatinine and albumin were found in the
tumour bearing dogs.
Description
TNV_TH_2016_MVM14060
Keywords
Veterinary Science