Real-time detection of Salmonella Typhimurium using optical fiber plasmonic biosensor based on surface plasmon resonance
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Date
2021-08
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G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand)
Abstract
Foodborne pathogens have remarkably caused food contamination at every stage of food production, processing, and distribution. Salmonella is one of the main organisms causing the outbreaks of foodborne illnesses, and pork is one of the major vehicles of foodborne salmonellosis throughout the world. It is therefore highly desirable that the presence of Salmonella Typhimurium be detected at the preprocessing stage of the product been made from any such source which may carry this bacteria and that may contaminate the product. In this thesis an optical fiber index sensor based on surface plasmon resonance is proposed for label-free and real-time detection of Salmonella Typhimurium. The sensing properties of the sensor are numerically simulated in COMSOL Multiphysics5.5. The first layer of silver nanoparticles is coated on the fiber probe sensor and the second layer as grapheme oxide. The reflection properties and the refractive index sensitivity of the sensor are systemically investigated. The results shows that by changing refractive index on the surface of multimode optical fiber gives a remarkable shift of resonance peak. In addition the proposed sensor is very easy to make and the layer of graphene oxide enhances the field to a great extent and also protect the silver film from oxidation. This refractive index sensor is highly sensitive and best choice for bio-medical applications.