MOLECULAR CHARACTERIZATION OF ANTIVIRAL MUSHROOMS FROM THE WESTERN GHATS OF KARNATAKA
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Date
2017-11-27
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UNIVERSITY OF AGRICULTURAL SCIENCES GKVK, BENGALURU
Abstract
Mushrooms are not only known for their nutritional properties but also for the
antiviral properties. Wild mushrooms (20) were collected from the Western Ghats of
Karnataka, identified and screened for antiviral properties in the present study. Edible
mushrooms (4) were also collected for screening against two animal viruses. Among
these mushrooms, one was identified as Ganoderma lucidum based on its phenotypic
characters and the other nineteen mushrooms were identified by ITS region sequence
using National Centre for Biotechnology Information (NCBI) GenBank as Lentinus sp.
(WGM-2), Pycnoporous sanguineus (WGM-03), Leucocoprinus birnbaumii (WGM-04),
Trametes versicolor (WGM-05), Pleurotus djamor (WGM-06), Auricularia sp.(WGM-
07), Termitomyces sp. (WGM-08), Laccaria vinaceoavellanea (WGM-09) Pluteus sp.
(WGM- 10), Gymnopilus lepidotus (WGM-11), Leucocoprinus cepistipes (WGM-12),
Leucoagaricus cf. majusculus (WGM-13), Microporus vernicipes (WGM-14) ,
Polyporales sp. (WGM-15), Agaricales sp. (WGM-16), Trametes elegans (WGM-17 ),
Pluteus cervinus (WGM-18), Micromphale foetidum (WGM-19) and Pluteus chryzaegis
(WGM-20).
Aqueous extracts of twenty wild mushrooms and four cultivated mushrooms were
screened against two animal viruses viz., Bovine Herpes Virus -1 (DNA virus) and Peste
des petits ruminants (PPR) virus (RNA virus). Among 24 mushrooms, only 4
mushrooms viz., Lentinus sp. (WGM-02), Pycnoporous sanguineus (WGM-03),
Leucocoprinus birnbaumii (WGM-04) and Trametes versicolor (WGM-05) extracts
showed antiviral activity against both the viruses. Ganoderma lucidium (WGM-01)
inhibited PPR virus and not BoVH-1 virus indicating its specificity and other mushrooms
did not exhibit antiviral activities.
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