CONTRAST ENHANCED ULTRASONOGRAPHY OF ABDOMEN IN DOGS
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Date
2019-12
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SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517502. (A.P.) INDIA
Abstract
The aim of the present study was to evaluate the normal and diseased organ perfusion by contrast enhanced ultrasound scanning (CEUS) in different abdominal organs of dogs. Contrast enhanced ultrasonography was conducted to compare the vascular and parenchymal perfusion using materials like SonoVue® and Definity® and compared with features plain, contrast radiography and ultrasonography . The present study was conducted on dogs with different abdominal disorders and signalment. A total of 210 cases of abdominal disorders were presented with different clinical signs and subjected to different diagnostic procedures. Among the diagnostic procedures, the radiography, ultrasonography and contrast radiography were considered as a diagnostic tools to study the abdominal disorders of different breeds and different organs. The cases with obscured lesion, even after using of all diagnostic aids, were randomly selected and subjected to contrast enhanced ultrasonography. Contrast enhanced ultrasonography of the liver, spleen, kidney and prostate gland was performed to characterize the perfusion of normal organs. To validate the quantification method, perfusion parameters (AT, TTPi, TTPa, DT and WOTi) were investigated using CEUS. The biological effects of CEUS on different organs were estimated by measuring and analyzing hematological and serum biochemical parameters to study the toxic effects of ultrasound contrast agents, if any. No changes were noted in the serum biochemistry profile after CEUS, with the exception of a small difference serum biochemistry which had no clinical importance. Finally, the role of contrast enhanced ultrasonography in disease diagnosis of different organs was investigated and confirmed by histopathological studies.
In conclusion, the results suggest that CEUS can be used also in veterinary patients as an additional diagnostics aid. The perfusion patterns found in the imaged organs were typical and similar to those seen earlier. Differences in the perfusion between organs corresponded with physiology in normal and disease condition. The results indicate that CEUS can be used safely to analyse organ perfusion in dogs.
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