EVALUATION OF THERAPEUTIC PROTOCOLS FOR THE MISALLIANCE AND INDUCTION OF WHELPING IN BITCHES
| dc.contributor.advisor | SADASIVA RAO, K(MAJOR) | |
| dc.contributor.advisor | SOLMON RAJU, K.G | |
| dc.contributor.advisor | RAGHAVENDER, K.B.P | |
| dc.contributor.advisor | GOPAL REDDY, A | |
| dc.contributor.author | RAM CHANDRA REDDY, K | |
| dc.date.accessioned | 2018-10-27T10:15:10Z | |
| dc.date.available | 2018-10-27T10:15:10Z | |
| dc.date.issued | 2009-06 | |
| dc.description.abstract | ABSTRACT : Study entitled “Evaluation of therapeutic protocols for the misalliance and induction of whelping in bitches” was conducted in teaching veterinary hospitals of Veterinary College (Bhoiguda, college campus hospital and Mylardevpalli). A total of 24 misalliance bitches and 29 advanced pregnant bitches were utilized to conduct this study. In misalliance bitches pregnancy was terminated 100% in three treatment groups. The incidence of abortion and resorption percentage in number of amniotic vesicles observed in ultrasound scanning at the beginning of treatment in mifepristone group was 15.38% & 84.62%, in cabergoline plus cloprostenol group was 0% & 100%, in cloprostenol group was 26.09% & 73.91% and in control group was 0% & 6.66% respectively. The side effects observed in misalliance treatment were vomition, salivation, dyspnoea, colic symptoms, vulval discharge and mammary gland enlargement. Total number of bitches that showed the side effects and their percentages were 36 (50%), 4(66.66%) and 5 (83.33%) in mifepristone, cabergoline plus cloprostenol and cloprostenol groups respectively. All bitches showed mild intensity of side effects i.e., < 5 score side effects. In no bitch termination of treatment was required due to the side effects. In mifepristone group higher progesterone concentrations were observed during pregnancy termination and in other group’s pregnancy termination was observed after reducing progesterone concentration to less than 2ng/ml. In control group progesterone levels were increasing as the progress of pregnancy. The average inter estrous cycle interval was 116.67 ± 5.9, 115.83 ± 2.89, 116.5 ± 2.13 and 146.0 ± 5.71 days in mifepristone, cabergoline plus cloprostenol, cloprostenol and control groups respectively. Treatment groups had significantly shorter inter estrous cycle interval then control group. The average number of pups born in the next whelping was 3.5 ± 0.22, 5.67 ± 0.33, 3.34 ± 0.55 and 5.0 ± 0.58 in mifepristone, cabergoline plus cloprostenol, cloprostenol and control groups respectively. Statistical analysis revealed that mifepristone group and cloprostenol group had significantly less number of pups than that of control group, whereas cabergoline plus cloprostenol group of bitches have given birth to significantly more number of pups. The mean gestation length in therapeutic groups at the time of initiation of treatment was 66.5 ± 1.2, 67.7 ± 0.58 and 65.14 ± 1.65 days in cloprostenol, dinoprostone plus cloprostenol, mifepristone plus cloprostenol groups respectively. Whereas, in control group gestation length calculated up to the whelping it was 62.67 ± 0.92 days. The mean duration of time interval from starting of treatment to beginning of whelping(hours) , duration of whelping( minutes) and inter pup intervals (minutes) were 34.46 ± 4.70, 490 ± 96.94 and 192.24 ± 62.58 respectively in cloprostenol group, 40.48 ± 6.47, 253.13 ± 47.87 and 67.67 ± 10.75 respectively in dinoprostone plus cloprostenol group and 26.98 ± 4.51, , 354 ± 85.59, 61.0 ± 9.41 respectively in mifepristone plus cloprostenol group. Whelping occurred in cloprostenol, dinoprostone plus cloprostenol and control groups when the mean plasma progesterone concentrations reached around 1.0ng/ml. But in mifepristone plus cloprostenol group is having higher progesterone level. Slight decrease in rectal temperature was observed 12 to 24 hours after treatment and again it reached to the normal level around 12 hours or less before parturition in cloprostenol, dinoprostone plus cloprostenol and control groups. But such change is not observed in mifepristone plus cloprostenol group. In this group rectal temperature remained constant from before treatment to up to whelping. The mean litter size at birth were 4.17 ± 1.08, 4.3 ± 0.82, 4.86 ± 1.2 and 7.5 ± 0.6, per centage of pup survival rate after one week was 95.23, 100, 93.24 and 90.74 and Percentage of growth rate recorded at the end of 1st week was 31.49%, 75.30% 65.365 and 65.61 in cloprostenol group, dinoprostone plus cloprostenol group, mifepristone plus cloprostenol group and control groups respectively. Mild side effects were observed in 83.33, 30 and 28.57 in percentage of bitches in cloprostenol, dinoprostone plus cloprostenol and mifepristone plus cloprostenol groups respectively. These side effects won’t cause termination of treatment in any bitch. Polydipsia was observed in cloprostenol, dinoprostone plus cloprostenol group bitches. The mean interval from whelping to next estrus cycle was 150.83 ± 10.27, 143.8 ± 9.55, 175.67 ± 12.39 and 140 ± 5.17 days and litter size in subsequent whelping were 4.83 ± 0.79, 6 ± 0.78, 5.67 ± 0.88 and 7 ± 0.32 in cloprostenol, dinoprostone plus cloprostenol, mifepristone plus cloprostenol and control groups respectively. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810082387 | |
| dc.keywords | BITCHES;THERAPEUTIC PROTOCOLS;MISALLIANCE ;INDUCTION ;WHELPING | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 199 | en_US |
| dc.publisher | SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA | en_US |
| dc.sub | Animal Reproduction and Gynecology | en_US |
| dc.subject | null | en_US |
| dc.theme | EVALUATION OF THERAPEUTIC PROTOCOLS FOR THE MISALLIANCE AND INDUCTION OF WHELPING IN BITCHES | en_US |
| dc.these.type | M.V.Sc. | |
| dc.title | EVALUATION OF THERAPEUTIC PROTOCOLS FOR THE MISALLIANCE AND INDUCTION OF WHELPING IN BITCHES | en_US |
| dc.type | Thesis | en_US |