“TOXICOPATHOLOGY OF ROSUVASTATIN AND THIAZOLIDINEDIONES (ROSIGLITAZONE AND PIOGLITAZONE) IN MALE RATS

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dc.contributor.advisorDr. D. J. Ghodasara
dc.contributor.authorPAWAR AALAP N.
dc.date.accessioned2017-06-23T05:30:29Z
dc.date.available2017-06-23T05:30:29Z
dc.date.issued2009
dc.description.abstractRosuvastatin is among of the most effective treatment of hyperlipidemia and dyslipidemia by providing an important and effective approach for lipid lowering agents. Thiazolidinediones (rosiglitazone and pioglitazone) are most commonly prescribed in patients with type 2 diabetes mellitus to lower blood glucose levels. The present research work was conducted to evaluate the repeated dose toxicity of rosuvastatin and thiazolidinediones (rosiglitazone and pioglitazone) in Sprague Dawley male rats. The animals were divided in 7 different groups with 6 male animals in each group. The groups I, II, III, and IV were administered vehicle control (0 mg/kg), rosuvastatin (50 mg/kg), rosiglitazone (80 mg/kg), and pioglitazone (300 mg/kg) in individual treatment groups respectively. The groups V, VI and VII were treated in different combinations with rosuvastatin (50mg/kg) + rosiglitazone (80mg/kg); rosiglitazone (40mg/kg) + pioglitazone (150mg/kg) and rosiglitazone (80mg/kg) + pioglitazone (300mg/kg) respectively by oral dosage for 28 days.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810022938
dc.keywordsTOXICOPATHOLOGY OF ROSUVASTATIN AND THIAZOLIDINEDIONES, MALE RATSen_US
dc.language.isoenen_US
dc.publisherAnand Agricultural University, Ananden_US
dc.research.problemTOXICOPATHOLOGY OF ROSUVASTATIN AND THIAZOLIDINEDIONES (ROSIGLITAZONE AND PIOGLITAZONE) IN MALE RATSen_US
dc.subVeterinary Pathologyen_US
dc.subjectVeterinary Pathologyen_US
dc.subjectStudyen_US
dc.themeTOXICOPATHOLOGY OF ROSUVASTATIN AND THIAZOLIDINEDIONESen_US
dc.these.typeM.V.Sc.en_US
dc.title“TOXICOPATHOLOGY OF ROSUVASTATIN AND THIAZOLIDINEDIONES (ROSIGLITAZONE AND PIOGLITAZONE) IN MALE RATSen_US
dc.typeThesisen_US
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