Multiple anthelmintic resistance in gastrointestinal nematodes of sheep in Southern India
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Date
2009
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Abstract
The occurrence of anthelmintic resistance on three institutional sheep farms in Tamil Nadu, India was
investigated using the Faecal Egg Count Reduction Test (FECRT) for both benzimidazoles and levamisole, the
egg hatch assay for benzimidazole (BZD) and Larval Migration Inhibition Assay (LMIA) for levamisole (LEV).
FECR value after treatment with albendazole and levamisole ranged from 69-80 and from 70-82 respectively
in the three farms examined. The ED50 values for TBZ in EHA for isolates from three farms were 0.627, 0.678
and 0.388 μg/mL of TBZ and the LM50 values in LMIA for the isolates from three farms were 0.707. 0.437
and 0.377 μg/mL of LEV. The results of the survey indicated multiple resistance in Haemonchus contortus
and Teladorsagia sp. to benzimidazoles and levamisole in farm I, simultaneous resistance in Teladorsagia
sp. to benzimidazoles and levamisole in farm II and simultaneous resistance in Haemonchus contortus to
benzimidazoles and levamisole in farm III.
Description
TNV_VA_2009_79(6)611-620
Keywords
Veterinary Science