DIAGNOSTIC AND THERAPEUTIC STUDIES ON POST PARTUM ANOREXIA WITH PARTICULAR REFERENCE TO HEPATIC INSUFFICIENCY IN COWS
Loading...
Files
Date
2009-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA
Abstract
ABSTRACT :
Out of a total of 291 anorexia cases presented to Campus Veterinary Hospital and Ambulatory clinic, Mylardevpally, Teaching Veterinary Clinical Complex, College of Veterinary Science, Rajendranagar, Hyderabad and Mekaguda village near Hyderabad only 68 (23.37%) crossbred cows were diagnosed based on history as post partum anorexia (PPA) cases. On detailed clinical examination and urinalysis of cases of PPA it was observed that 30 (44.12%) cows had PPA with hepatic insufficiency which formed about 10.31 per cent of total cases of anorexia.
Ten apparently healthy cows which were in same post partum period but showing no clinical signs were selected to serve as control group for working out the normal values. Thirty clinical cases of PPA with hepatic insufficiency selected on the above basis were subjected to detailed clinico-biochemical examination and therapeutic trial. The clinical cases exhibited various symptoms like partial to complete loss of appetite, decreased milk yield in 93.33 per cent cows, dull and depression in 76.66 per cent cows, scanty and pasty dung in 60 per cent of cows, reduced ruminal motility in 76.66 per cent of cows, rough coat in 30 per cent cows and symptoms such as lacrimation, nasal discharges and cough in 16.66 per cent of cows. Passing of clay coloured dung was observed only in four cows. Thirty clinical cases of cows suffering from PPA with hepatic insufficiency were randomly divided in to three groups of 10 animals in each. Cows of group I were treated orally with two boli of Zigbo (M/S Natural Remedies Private Ltd., Bangalore, India) and two boli of Ecotas (M/S Intas Pharmaceutical Ltd., Ahmedabad, India) daily for five days. Group II cows were administered Inj. Livadex forte 10ml i/m (M/S Virbac Animal Health India Pvt. Ltd., Mumbai, India) and two boli of Ecotas orally daily for five days while all the cows belonging to group III were treated Inj. Livadex forte 10 ml i/m, two boli of Zigbo and two boli of Ecotas orally daily for five days. The serum samples were collected before and after completion of treatment for estimation of serum glucose, total protein, albumin, AST, ALP and GGT. The urine samples, similarly collected were analysed for Rothera’s test for ketones, sulkowitch test for calcium, Ehrlich’s test for urobilinogen, Methylene blue test for bilirubin and Hay’s test for urinary bile salts. There was no significant difference in the temperature, pulse and respiration rates of all the groups before and after treatment on comparison with healthy control values, but whereas rumen motility was significant (P < 0.05) increased after treatment in group I, II and (P < 0.01) group III. In cows of group I the serum glucose, total protein and albumin values were increased and AST, ALP, GGT values were decreased after therapy, but all these biochemical parameters were not statistically significant, feed and water intake and milk yield were returned near to pre disease level. In cows of group II the serum glucose, total protein and albumin values were increased and AST, ALP, GGT values were decreased after therapy. There was significant (P < 0.05) difference in the mean values of these biochemical parameters except serum glucose, which was not significant statistically, milk yield returned to pre disease level. After completion of treatment the general condition of cows of group III improved and active. Feed and water intake and the milk yield were returned to pre disease level. There was significant (P < 0.01) increase in mean values of total protein and albumin and significant (P < 0.01) decrease in mean values of AST, ALP and GGT. Though there was increase in serum glucose after treatment but was not significant statistically. From the above findings it was concluded that crossbred cows of PPA with hepatic insufficiency could be treated successfully with a combination of Zigbo bolus, Ecotas bolus and Inj. Livadex forte for quick and complete recovery.
Description
THESES
Keywords
null