DIAGNOSTIC AND THERAPEUTIC STUDIES ON CHRONIC RENAL FAILURE IN DOGS
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Date
2009-02
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SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA
Abstract
ABSTRACT:
The aim of the study was to find out the incidence of Chronic Renal Failure (CRF) in dogs with relation to age, breed and sex in and around Tirupati, to study the clinical, haematological and biochemical profile in dogs with CRF, to study ultrasonographic findings in dogs with CRF and to formulate an effective therapeutic regimen for CRF in dogs. The study revealed higher incidence of CRF in spitz with male predominance and in age group of 8-12 years. Clinical examination of CRF cases revealed anorexia, vomiting, dullness, weight loss, oral ulcers, polyuria, polydipsia, pale mucous membrane, melena, recumbency and blindness. Blood pressure measurement showed significant elevation of systolic arterial pressure in CRF dogs. Haematological values showed the results of anemia and mild neutrophilic leucocytosis. In serum biochemical profile, elevated serum urea nitrogen, creatinine, phosphorous, sodium and normal serum potassium and calcium were observed. However decreased total protein and albumin levels were observed in CRF dogs compared to apparently healthy dogs. Urinalysis showed normal pH, decreased specific gravity and elevated urine protein and creatinine ratio and urinary enzymes (ALP and GGT) excretion. Nephrosonography revealed hyperechoic renal cortex, hyperechoic medulla, indistinct corticomedullay junction and sunken kidneys in CRF dogs. Combination of root extract of B.diffusa and conservative treatment was found to be effective in the therapeutic management of CRF in dogs.
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