Cytopathological and immunohistochemical assessment of mammary tumors in male dogs

dc.contributor.authorPrabhakaran, KP
dc.contributor.authorBalasubramaniam, GA
dc.contributor.authorMadheswaran, R
dc.contributor.authorRaja, A
dc.contributor.authorTANUVAS
dc.date.accessioned2021-02-17T05:57:15Z
dc.date.available2021-02-17T05:57:15Z
dc.date.issued2020
dc.descriptionTNV_IJVP_2020_44(1)7-10en_US
dc.description.abstractThree male dogs aff ected with mammary tumors brought for treatment were aged 7 to 10 years. Tumor was noted at right caudal thoracic in one dog and left caudal thoracic region in two dogs. The mean haemato-biochemical parameters revealed no alterations except leucocytosis associated neutrophilia and elevated blood urea nitrogen and creatinine. The serum sex hormones estradiol and progesterone were increased, whereas, testosterone values were unaltered. Grossly, cut surface of the tumor mass from one dog revealed greyish white, blood tinged and caulifl ower like growth. Fine needle aspiration smears revealed neoplastic cells mixed with infl ammatory cells. Histopathologically the tumor mass revealed extensive proliferation of dense fi brous tissue, area of chondroid diff erentiation and transformation of fi broblast into cartilage. Proliferating neoplastic cells showed degeneration, necrosis and infi ltration of infl ammatory cells. Immunohistochemical analysis of tumor tissues revealed triple negative phenotype for estrogen and progesterone receptors and Human Epidermal Growth Factor-2, but positive reaction for cytokeratin. Clinico-pathological investigations and immunohistochemical features were consistent in diagnosis of mammary tumors in male dogs.en_US
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810161281
dc.keywordsMale dogs, mammary tumors, cytopathology, immunohistochemistryen_US
dc.language.isoEnglishen_US
dc.pages7-10en_US
dc.relation.ispartofseries;1
dc.subjectVeterinary Scienceen_US
dc.titleCytopathological and immunohistochemical assessment of mammary tumors in male dogsen_US
dc.title.alternativeIndian Journal of Veterinary Pathologyen_US
dc.typeArticleen_US
dc.volume44en_US
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