CLINICO-DIAGNOSTIC AND THERAPEUTIC STUDIES ON ANAPLASMOSIS IN BUFFALOES
| dc.contributor.advisor | SURESH .K (MAJOR) | |
| dc.contributor.advisor | CHAITANYA .Y | |
| dc.contributor.advisor | HARI KRISHNA .N.V.V | |
| dc.contributor.author | LIKITHA .N | |
| dc.date.accessioned | 2024-07-08T07:34:06Z | |
| dc.date.available | 2024-07-08T07:34:06Z | |
| dc.date.issued | 2024-03 | |
| dc.description.abstract | The present study entitled “Clinico-diagnostic and therapeutic studies on anaplasmosis in buffaloes” was taken up to record the occurrence, clinical signs, haemato biochemical alterations and to evaluate suitable therapeutic regimen in buffaloes affected with anaplasmosis in and around Gannavaram during the period from March 2023 to November 2023. The overall occurrence of anaplasmosis recorded in the present study was 29.17 per cent with respect to the total number of buffaloes screened. Occurrence of anaplasmosis with respect to age, gender and breed revealed highest per cent occurrence in buffaloes of ≥7 years, females and Graded Murrah buffaloes respectively. Diagnosis of anaplasmosis was done based on clinical signs, examination of Leishman’s-stained blood smears and PCR. Clinical signs recorded include inappetence to anorexia, paleness of mucous membrane, icterus, reduced milk yield, fever, lymph node enlargement, emaciation, dyspnoea, diarrhoea, ocular discharges, brown coloured urine and/or abortions. Examination of Leishman’s-stained blood smear revealed Anaplasma marginale organism as dense, uniformly pigmented blue-purple inclusions near the margin of erythrocytes. Molecular detection of Anaplasma marginale was done by PCR which revealed an expected amplicon size of 457 bp. In the present study, PCR was found to be ideal for the diagnosis of anaplasmosis. Clinical examination revealed significant increase in mean temperature, respiratory rate and heart rate in animals affected with anaplasmosis when compared with healthy control group while the ruminal motility was decreased significantly. Haematological examination in buffaloes affected with anaplasmosis revealed significant decrease in mean Hb, PCV and TEC count while TLC showed non-significant decrease. Leucogram revealed neutrophilia, lymphocytopenia and eosinophilia. Serum biochemical examination revealed significant increase in the levels of ALT, AST, ALP, globulin and total bilirubin while glucose and albumin decreased significantly as against healthy control. Therapeutic trial was undertaken in 19 out of 21 buffaloes diagnosed as anaplasmosis, by randomly dividing them into two groups with 10 in Group I and 9 in Group II. Group I animals were treated with oxytetracycline for 5 days while Group II animals were treated with imidocarb twice with an interval of one week. In animals of both the groups, single dose of ivermectin was administered. Supportive therapy was continued with Syrup 3D red, Syrup E care Se and Livotas suspension for a period of 21 days. Both the therapeutic regimens were proven to be efficacious in the treatment of anaplasmosis caused by Anaplasma marginale based on resolution of clinical signs and improvement in the haemato-biochemical parameters. However, imidocarb could be preferred because of less average clinical recovery time when compared to oxytetracycline. | |
| dc.identifier.uri | https://krishikosh.egranth.ac.in/handle/1/5810211586 | |
| dc.language.iso | English | |
| dc.pages | 166 | |
| dc.sub | Veterinary Medicine | |
| dc.theme | CLINICO-DIAGNOSTIC AND THERAPEUTIC STUDIES ON ANAPLASMOSIS IN BUFFALOES | |
| dc.these.type | M.V.Sc. | |
| dc.title | CLINICO-DIAGNOSTIC AND THERAPEUTIC STUDIES ON ANAPLASMOSIS IN BUFFALOES | |
| dc.type | Thesis |