ANTI-PROLIFERATIVE ACTIVITY OF TINOSPORA CORDIFOLIA DETERMINED BY CELL COUNT AND TRYPAN BLUE DYE EXCLUSION METHOD IN MCF-7 CELLS

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dc.contributor.authorSakthi Priya, M
dc.contributor.authorVenkataramanan, KV
dc.contributor.authorMathuram, LN
dc.contributor.authorParthiban, M
dc.contributor.authorVijayanand, T
dc.contributor.authorTANUVAS
dc.date.accessioned2020-01-14T11:01:08Z
dc.date.available2020-01-14T11:01:08Z
dc.date.issued2013
dc.descriptionTNV_IJBIO_2013_2(4)719-722en_US
dc.description.abstractAn in-vitro study was performed in mammary tumor cell line MCF-7 to find out the antiproliferative activity of aqueous and hydro-alcoholic extracts of Guduchi Tinospora cordifolia, each at three different doses viz., 200μg/ml, 400μg/ml and 600μg/ml. Their effects on the proliferation of cells were analyzed by cell count assay and cell viability was detected by using trypan blue dye exclusion method. Both of the extracts produced significant decrease in cell count and cell viability, with maximum effect being noticed at the dose level of 600μg/ml. This result suggest that aqueous and hydro-alcoholic extracts of Tinospora cordifolia could reduce cell count and cell viability in MCF-7 cell line and act as effective anti-proliferative agent in mammary tumor.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810140440
dc.keywordsTinospora cordifolia, Anti-proliferative activity, MCF-7cell line, Cell count, Trypan blue.en_US
dc.language.isoenen_US
dc.pages719-722en_US
dc.relation.ispartofseries;4
dc.subjectVeterinary Scienceen_US
dc.titleANTI-PROLIFERATIVE ACTIVITY OF TINOSPORA CORDIFOLIA DETERMINED BY CELL COUNT AND TRYPAN BLUE DYE EXCLUSION METHOD IN MCF-7 CELLSen_US
dc.title.alternativeInternational Journal of Bioassaysen_US
dc.typeArticleen_US
dc.volume2en_US
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