Toxic and anti-fertility effect of Calotropis procera leaf extract on Bandicota bengalensis
| dc.contributor.advisor | Babbar, B.K. | |
| dc.contributor.author | Kiran Rani | |
| dc.date.accessioned | 2020-01-16T09:06:55Z | |
| dc.date.available | 2020-01-16T09:06:55Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Calotropis procera has strong insecticidal, fungicidal, toxic (hepatotoxic, nephrotoxic and cardiotoxic) and anti-fertility effects But no data is available regarding its toxic and antifertility effect on male Bandicota bangalensis. Three different C. procera dry leaf powder extract and fresh leaf juice based treated baits were tested against male bandicoot rat, B. bengalensis in bi-choice feeding tests. Results demonstrated no lethal or acute toxic effects with all C. Procera leaf based treated baits when given to rats continuously for three days. Therefore, the duration of experiment was increased to 30 days to determine the anti-fertility and chronic toxicity effects of same treated baits as used in acute toxicity determination experiment. There was a significant reduction in consumption (g/100 g b wt.) of treated baits as compared to untreated bait. Out of three treated baits, average consumption of active ingredient was maximum with treated bait 2 and percent acceptance of this bait ranged from 47.66 % to 60.67 %. Results also revealed significant reduction in the weights of male reproductive organs (testes, cauda epididymis, corpus epididymis and caput epididymis), sperm motility, viability and sperm concentration and increase in sperm abnormalities in rats fed on treated bait 2. The histomorphological study of testis revealed significant reduction in the diameter of seminiferous tubules and thickness of germinal epithelium because of reduction in number of both germ and Sertoli cells in different stages of seminiferous epithelial cycle in rats fed on treated bait 2 indicating efficacy of treated bait 2 as antifertility agent. However nephrotoxic effect and oxidative stress was not recorded in same rats fed on treated bait 2. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810140528 | |
| dc.keywords | Calotropis procera, Bandicota bengalensis, percent acceptance, antifertility, nephrotoxic | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 98 | en_US |
| dc.publisher | Punjab Agricultural University, Ludhiana | en_US |
| dc.research.problem | Toxic and anti-fertility effect of Calotropis procera leaf extract on Bandicota bengalensis | en_US |
| dc.sub | Zoology | en_US |
| dc.subject | null | en_US |
| dc.theme | Toxic and anti-fertility effect of Calotropis procera leaf extract on Bandicota bengalensis | en_US |
| dc.these.type | M.Sc | en_US |
| dc.title | Toxic and anti-fertility effect of Calotropis procera leaf extract on Bandicota bengalensis | en_US |
| dc.type | Thesis | en_US |