Comparative immunoprophylactic efficacy of Haemonchus contortus recombinant enolase (rHcENO) and Con A purified native glycoproteins in sheep

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dc.contributor.authorAravindhan, K.
dc.contributor.authorJawahar, Shabnam
dc.contributor.authorManikkavasagan, I.
dc.contributor.authorAzahahianambi, P.
dc.contributor.authorRaman, M.
dc.contributor.authorTANUVAS
dc.date.accessioned2019-07-22T11:39:29Z
dc.date.available2019-07-22T11:39:29Z
dc.date.issued2015
dc.descriptionTNV_EP_154_2015_98en_US
dc.description.abstractHaemonchus contortus is the most economically important blood feeding nematode parasite of sheep and goats all over the world. Enolase in helminth parasites is a multi-functional enzyme which involves in glycolysis and host tissue invasion. In this study, the recombinant H. contortus enolase (rHcENO) was evaluated for its immunoprophylactic efficacy in sheep along with Con A purified native glycoproteins in a vaccine challenge trial. Group I and Group II experimental sheep were immunized thrice with rHcENO and Con A purified native glycoproteins along with Montanide ISA 61 VG adjuvant. The animals were challenged with 5000 L3 stage active H. contortus larvae after 21 days of third immunization. A significant increase in the IgG titre was observed in rHcENO and Con A purified native glycoproteins immunized animals as compared to the control animals. Immunoprotective efficacy of Con A purified native glycoproteins was comparatively higher than rHcENO antigen.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810116131
dc.keywordsVeterinary Science, Veterinary Parasitology, Haemonchus contortus, Enolase, Con A purified native glycoproteins, rHcENO, Vaccine, Sheepen_US
dc.language.isoen_USen_US
dc.pages98en_US
dc.subjectVeterinary Scienceen_US
dc.subjectVeterinary Parasitologyen_US
dc.titleComparative immunoprophylactic efficacy of Haemonchus contortus recombinant enolase (rHcENO) and Con A purified native glycoproteins in sheepen_US
dc.typeArticleen_US
dc.volume154en_US
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