Quinolone Arthropathy in Broiler Chicken Administered with Enrofloxacin
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Date
2019-02
Journal Title
Journal ISSN
Volume Title
Publisher
Pashupati Foundation India
Abstract
Arthropathic potential of enrofloxacin was investigated in broiler chicken at recommended therapeutic
dose. Day old broiler chicks were randomly divided into 4 groups each comprising 6 birds. Group I, control
birds received non medicated water, while group II, III, IV and V were medicated with enrofloxacin at
recommended therapeutic dose 10mg/Kg body weight in drinking water for 5 successive days from 43rd to
47th day of age. Juvenile cartilages were collected on 1, 3, 5 and 9 days after the last dose from respective
treatment groups and subjected to histopathological examination. Degeneration of chondrocytes was
noticed in day 1 post treatment group and shrunken chondrocytes with pyknotic nuclei were observed till
5th day post treatment. However, clumping of chondrocytes observed on day 5 post treatment and a few
cases of degenerated chondrocytes on day 9 post treatment around the blood vessels, suggestive of reversal
in chondrocyte lesions.
Description
TNV_IJLR_2019_9(2)211-216
Keywords
Veterinary Science