EPIDEMIOLOGICAL STUDIES ON PESTE DES PETITS RUMINANTS IN CERTAIN PARTS OF ANDHRA PRADESH

dc.contributor.advisorSHOBHAMANI, B (Major)
dc.contributor.advisorSREEDEVI, B
dc.contributor.advisorSREENIVASULU, D
dc.contributor.authorSARITHA, G
dc.date.accessioned2016-12-30T20:12:01Z
dc.date.available2016-12-30T20:12:01Z
dc.date.issued2011
dc.description.abstractAbstract: Peste des petits ruminants (PPR) is an acute highly contagious and rapidly spreading transboundary viral disease of sheep and goats. The disease is associated with high morbidity and mortality in susceptible animals. It causes severe losses to small ruminant production. Hence a modest attempt has been made to study PPR in Andhra Pradesh with respect to epidemiological status, sero-prevalence, antigen detection and evaluation of efficacy of PPR live attenuated vaccine. The sero-prevalence of PPR was studied by screening 803 sera samples from sheep (398) and goats (405) belonging to 5 different districts of Andhra Pradesh during the period from December 2010 to April 2011. The overall sero-prevalence of PPR in sheep and goat of the present study was 67.87 per cent. Among the districts sero-prevalence ranged from 49.25 to 89.07 per cent. Species wise sero-prevalence of PPR in sheep and goats was 65.32 and 70.37 per cent, respectively. The sero-prevalence was higher (80.65%) in 13-45 months old followed by 4-12 months (67.83%) old sheep and goat. Out of 195 clinical samples (nasal swabs and tissues) tested, the PPR antigen was detected in 66 samples with an overall prevalence of 33.84 per cent. The antigen prevalence (tissues and swabs) was relatively higher (34.52%) in goats than in sheep (33.33%). In the present study 47 flocks (94%) were found positive for PPR antibodies out of 50 flocks (sheep and goats) screened, whereas both the antigen and antibody were detected in 29 flocks (69.04%) out of 42 flocks tested. However in 3 flocks neither antigen nor antibody was detected. Reference vaccine virus as well as clinical samples, including nasal swab and liver tissue showed amplification of approximately 351 bp which is specific to PPRV. However no amplification was observed in the nasal swab collected from apparently healthy sheep. Antibody response to PPR live-attenuated vaccine was studied at Livestock Research station, Palamaner. Results showed that mean PI values in all age groups (G-I, G-II and G-III) gradually increased until 90 days (maximum period of observation) of post immunization, indicating initiation of antibody response to vaccine in field condition. Further studies are required to determine the duration of immunity of PPR live attenuated vaccine.en_US
dc.description.sponsorshipDepartment of Veterinary Epidemiology and Preventive Medicine, College of Veterinary Science, Tirupati – 517 502.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/93758
dc.language.isoenen_US
dc.publisherSri Venkateswara Veterinary University, TIRUPATI – 517 502,A.Pen_US
dc.subVeterinary Epidemiology and Preventive Medicine
dc.subjectRUMINANTS; EPIDEMIOLOGICAL STUDIES; PESTE DES PETITS RUMINANTS; PPR; sheep; goatsen_US
dc.these.typeM.V.Sc
dc.titleEPIDEMIOLOGICAL STUDIES ON PESTE DES PETITS RUMINANTS IN CERTAIN PARTS OF ANDHRA PRADESHen_US
dc.title.alternativeMVSC;CVSc;TPTY; Acc No:T1415en_US
dc.typeThesisen_US
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