Synthesis and Pesticidal Activity of 1,3,4‐ Thiadiazole derivatives
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Date
2012
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
IARI, DIVISON OF AGRICULTRAL CHEMICALS
Abstract
1,3,4-Thiadiazole and its derivatives are important organic reaction
intermediates and widely used by the chemists in the past to explore its biological
activities. One of the starting material, 5-methyl-1,3,4-thiadiazole-2-thiol is a part of
well known antibiotic, Cefazolin Sodium. Therefore, a series of 1,3,4-thiadiazole
derivatives have been synthesized using an appropriate synthetic route starting from
5-methyl/amino-1,3,4-thiadiazole-2-thiols and characterized by physico-chemical and
spectral data. The synthesized compounds were further taken up for their antifungal,
antinemic and nitrification inhibitory activities.
Description
T-8741
Keywords
5-methyl-1,3,4-thiadiazole-2-thiol, 5-amino-1,3,4-thiadiazole-2-thiol, 1,3,4-thiadiazole