CLINICAL EVALUATION OF ETOMIDATE AND PROPOFOL ANAESTHESIA FOLLOWING ATROPINE, DIAZEPAM AND FENTANYL PREMEDICATION IN GERIATRIC DOGS
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Date
2016-11
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SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA
Abstract
ABSTRACT:
Twelve dogs aged between 7-14 years of either sex presented to the college
clinic with surgical conditions like pyometra, urethral calculi, fractures and mammary
tumours were utilized to study the effect of etomidate and propofol after
premedication with atropine sulphate, diazepam and fentanyl. The animals were
divided into two groups of six animals each. Etomidate @ 0.3 mg/kg b.wt was given
intravenously in group I dogs. Propofol @ 6 mg/kg b.wt. intravenously was given in
group II dogs.
Induction quality was excellent, smooth and attained sternal recumbency
rapidly without struggling in all animals in both groups.Recovery from anaesthesia is
smooth and excitement free in both groups. However, slightly prolonged recovery
was a consistent observation in propofol group. No significant difference was noticed
in RT, RR, PR and SpO2 values between the groups. Non significant decrease in heart
rate was observed in dogs subjected to etomidate anaesthesia. A significant decrease
in heart rate was observed in group II dogs subjected to propofol anaesthesia. ECG
studies did not reveal any abnormality except increase in amplitude of QRS complex
duration in both groups.
The haematological parameters like Hb, PCV were differed significantly
within the group and between the groups. However, all the fluctuations were within
the normal physiological range. Changes in biochemical parameters like AST, ALT
and AKP were significant between the groups and were within the normal
physiological range in both groups.
Etomidate with atropine, diazepam and fentanyl premedication provided better
surgical anaesthesia with smooth induction and rapid, safe and smooth recovery in
geriatric dogs.
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