.DEVELOPMENT OF ENTERAL FORMULATIONS FROM NATURAL SOURCES INTENDED TO ENHANCE IMMUNE STATUS
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Date
2007-02-28
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University of Agricultural Sciences GKVK, Banglore
Abstract
Nutri tion has profound effects on immunity. Several nutrients have been
shown to influence immunologic and inflammatory responses in humans. Currently,
the interest is focused on the role of specific dietary components that could influence
the immune status of the body. These immuno nutrients comprises mainly essential
amino acids, micronutrients like zinc , selenium, iron, bet a-carotene , lycopene and n3
fatty acids. These nutrients enha nce cellular immunity, modul ate tumour cell
metab olism and cytoki ne production, augment lymphocyte and macrophage
proliferation 111 the immunocompromised subjects. But unfortunately, the
formulations that present in the market with such an immunonutrient composition
are usua lly expensive. As an alterna tive to it the present study aims at developing
two form ulations using natural produce namely carrots and tomatoes as a source of
antioxidants like beta-carotene and lycopene respectively.Soyprotein isolates (SPI)
and Whey protei n concentrate(WPC) were used as source of proteins. WPC being
rich in semi-essential amino acid cysteine also supplements to the immune
enhancing properties of the formulation. The formulations will provide17-18g
protein, 5g fat and around 400kcal per 100g.The micronutrient composition of the
formulations are: 5-7mg zinc, 250-31Omg calcium and 100-190mg magnesium per
100g.The cost of these formu lations are comparatively cheaper than those available
in the market and will be equally effective in enhancing the immune status in the
immunocompromised subjects.
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