CHARACTERIZATION OF MACROPINOCYTIC ABILITY OF CAPRINE ANTIGEN PRESENTING CELLS

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Date
2006-02
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Abstract
Macropinocytosis is an endocytic process by which large pinocytic vesicles are generated which sample extracellular fluids and solutes (Rescigno et al. 1999). Macropinocytosis provides an efficient sampling mechanism for fluid phase or non- binding antigens. Since macropinosomes have lower surface/volume ratios than mall vesicles, more extracellularfluid is sampled per unit membrane internalized (Steinman and Swanson, 1995).
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Veterinary Science, Veterinary Microbiology
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