CLINICO-PATHOLOGICAL STUDIES ON CANINE PYOMETRA
| dc.contributor.advisor | ANNAPURNA, P(MAJOR) | |
| dc.contributor.advisor | RAMA DEVI, V | |
| dc.contributor.advisor | RAVI KUMAR, P | |
| dc.contributor.author | SOLMON SINGH, B | |
| dc.date.accessioned | 2019-07-09T08:18:33Z | |
| dc.date.available | 2019-07-09T08:18:33Z | |
| dc.date.issued | 2018-12 | |
| dc.description | THESES | en_US |
| dc.description.abstract | The present study was undertaken at NTR College of Veterinary Science, Gannavaram to know the incidence, to carry out hematological, biochemical and bacteriological studies and to describe the lesions in canine pyometra. During the period of study, out of 140 bitches presented to Department of Surgery and Radiology at Teaching Veterinary Clinical Complex (TVCC) for various ailments, 20 bitches (14.3%) were diagnosed with pyometra by clinical examination, radiography and ultrasonography and various samples collected from these were used for further studies carried out in the present study. Highest incidence of pyometra (70%) was found in the age group of 6-10 years and the mean age of occurrence was 8.05 ± 0.61 years. Among the breeds, Pomeranian (35%) was mostly affected followed by Labrador (30%), Spitz (15%), German Shepherd (10%) and Boxer and Pug breeds (5% each). Nulliparous bitches (65%) were mostly affected followed by primiparous (25%) and pleuriparous (10%) animals. Open (85%) and closed (15%) types of pyometra were noticed and all the bitches were in diestrus. Anorexia, lethargy, vomition and normal temperature were observed in most of the cases. Mucopurulent to hemorrhagic vaginal discharges with fetid odour were seen in all open pyometra cases. In the present study, a significant decrease was noticed in the mean values of PCV, Hb and TRBC in pyometric bitches compared to control animals whereas no significant change was seen in MCV, MCH and MCHC that indicated a normocytic, normochromic anemia. Significant leucocytosis with regenerative shift to left was noticed. Significant increase was noted in the mean values of BUN, creatinine and AST and ALT in pyometric bitches compared to control dogs that indicated an altered renal and hepatic function respectively. The lesions noticed in the hysterectomised uteri from 20 pyometric bitches were grouped into types II, III and IV. Type II lesions (75%) consisted of open and closed pyometra. Grossly, horns were uniformly distended and revealed whitish cysts on the surface that exuded creamy pus on incision. Histopathologically, marked infiltration of plasma cells along with cystic glandular hyperplasia was characteristic. Myometrium revealed necrosis, plasma cell infiltration and showed adenomyosis in one case. Type III lesions (20%) consisted of open pyometra cases that showed marked sacculations of uterine horns grossly. Annular constrictions, whitish cysts, focal hemorrhages and ulceration were seen on cut section. Histopathologically, marked infiltration of polymorphs in the endometrial stroma and within glandular lumen was the consistent finding. Endometrial glands showed necrotic debris with bacterial colonies in the lumen and prominent periglandular fibrosis. Myometrium showed fibrosis and atrophy. A single open pyometra case (5%) with type IV lesion was noticed that showed highly distended uterine horns especially at the ovarian end. On cut section, granular endometrial surface and creamy white fluidy contents were noticed. Histopathologically, very thin endometrial layer with few cystic glands, stromal infiltration with mononuclears and atrophy and fibrosis of myometrium were observed. In the present study, a total of 6 isolates viz. E.coli (30%), Klebsiella sp. (20%), Pseudomonas sp. (15%), Shigella sp. (10%), S.aureus (10%), and Proteus sp. (5%) were obtained in pure cultures from 18 uterine samples whereas a mixed culture of E.coli with Shigella was obtained from two samples (10%) and E.coli was found to be the most common bacteria isolated from pyometra cases. The clinico-pathological studies on canine pyometra were carried out in the present study. The hematological and biochemical changes and the lesions noticed in pyometric bitches were characteristic and E.coli was the most predominant organism isolated from cases of pyometra. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810113424 | |
| dc.keywords | CANINE;PYOMETRA;CLINICO-PATHOLOGICAL | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 127 | en_US |
| dc.publisher | SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517502. (A.P.) INDIA | en_US |
| dc.sub | Veterinary Pathology | en_US |
| dc.subject | null | en_US |
| dc.theme | CLINICO-PATHOLOGICAL STUDIES ON CANINE PYOMETRA | en_US |
| dc.these.type | M.V.Sc. | en_US |
| dc.title | CLINICO-PATHOLOGICAL STUDIES ON CANINE PYOMETRA | en_US |
| dc.type | Thesis | en_US |