Assessment of the Immune Status in “Withaferin A” Treated Rats in Experimental Mammary Carcinogenesis by Flow Cytometry

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dc.contributor.authorPratheepa, K.
dc.contributor.authorBalachandran, C.
dc.contributor.authorVijaya, K.
dc.contributor.authorTANUVAS
dc.date.accessioned2018-01-31T09:06:49Z
dc.date.available2018-01-31T09:06:49Z
dc.date.issued2018-01
dc.descriptionTNV_IVJ_Jan2018_V95_I01_33-35en_US
dc.description.abstractThe present study was carried out to evaluate the immunomodulatory effect of Withaferin A in DMBA (7,12-dimethylbenz[a]anthracene) induced mammary carcinogenesis in rats. Twenty four female Sprague-Dawley (SD) rats were equally distributed to control, DMBA, DMBA+Tamoxifen (Standard drug) and DMBA+Withaferin A groups. Peripheral blood was collected at the 120th day from the initial dose of DMBA and CD3, total T lymphocytes were determined by using  ow cytometry. There was signi cant (P<0.05) increase in the total T lymphocytes (CD3) in the DMBA+Withaferin A group from DMBA+Tamoxifen group indicating immunostimulatory effect of Withaferin A.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810040165
dc.keywordsCD3 T lymphocytes, DMBA, Mammary carcinogenesis, Withaferin Aen_US
dc.language.isoenen_US
dc.pages33-35en_US
dc.publisherTANUVASen_US
dc.relation.ispartofseries;01
dc.subjectVeterinary Scienceen_US
dc.titleAssessment of the Immune Status in “Withaferin A” Treated Rats in Experimental Mammary Carcinogenesis by Flow Cytometryen_US
dc.title.alternativeIndian Veterinary Journalen_US
dc.typeArticleen_US
dc.volume95en_US
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