Glyphosate induced alterations in Cyprinus carpio (Linn.)

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dc.contributor.advisorHundal, S.S.
dc.contributor.authorBawa, Veenu
dc.date.accessioned2017-06-15T07:32:20Z
dc.date.available2017-06-15T07:32:20Z
dc.date.issued2016
dc.description.abstractThe present study was conducted to evaluate the effect of glyphosate (herbicide) to a commercially important fish, Cyprinus carpio (Linn.).Glyphosate is formulated as N- phosphonyl glycine in Roundup® which is a broad-spectrum, non-selective herbicide used for inhibition of unwanted weeds and grasses in agricultural, industrial, urban, forestry and aquatic landscapes. The 96 hour median lethal concentration (LC50) and effective concentration (EC50) values of glyphosate (Roundup® 41% SL) for fish fingerlings (mean wt. 3g ±0.5 and mean length 5.5cm ±0.35) were calculated. The fingerlings were exposed to two sublethal concentrations of glyphosate i.e. 25% of LC50 (T1) and 50% of LC50 (T2) for a period of 28 days. Biochemical parameters like proteins, lipids, AST (aspartate amino transferase) and ALT (alanine aminotransferase) in liver while proteins and lipids in muscle were estimated at weekly intervals. Histopathology of liver was also studied. The 96 hour LC50 and EC50 values were found to be 3.260 ppm and 0.509 ppm, respectively. The fish showed abnormal behaviour viz. air gulping, erratic swimming, rolling movement, restlessness, lack of balance and sudden fast movement. Proteins and lipids showed a significant (p>0.05) decline in both liver and muscle with increasing concentration and duration of exposure. However, the enzymatic activities of hepatic AST and ALT revealed a significant (p>0.05) increase with increasing concentration and period of exposure. Vacuolation of hepatocytes, fatty degeneration, pyknotic nuclei, degeneration of cytoplasm, infiltration of leukocytes, necrosis and severe vasodilation was noticed in the liver of exposed fish as compared to the control.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810020448
dc.keywordsAminotransferases, Cyprinus carpio, glyphosate, herbicide, histopathology, lipids, proteinsen_US
dc.language.isoenen_US
dc.pages59en_US
dc.publisherPunjab Agricultural University, Ludhianaen_US
dc.research.problemGlyphosate induced alterations in Cyprinus carpio (Linn.)en_US
dc.subZoologyen_US
dc.subjectnullen_US
dc.themeCyprinus carpioen_US
dc.these.typeM.Scen_US
dc.titleGlyphosate induced alterations in Cyprinus carpio (Linn.)en_US
dc.typeThesisen_US
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