Efficacy of Articaine and Ropivacaine as Local Anaesthetic for Paravertebral Analgesia in Cattle
Loading...
Date
2020-11-25
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
MAFSU, Nagpur
Abstract
The present research work on efficacy of articaine and ropivacaine as
local anaesthetic for paravertebral analgesia in cattle was conducted. A total
36 clinical cases of cattle reported at TVCC with various abdominal affections
were subjected for laparo rumenotomy. These clinical cases were randomly
divided into three equal groups (n=12) viz., Group 1 (2% Lignocaine HCl with
vasoconstrictor @ 4 mg/kg.b.wt.) in Group 2 (4% Articaine HCl with
vasoconstrictor @ 4 mg/kg.b.wt.) and in Group 3 (0.75% Ropivacaine HCl
with vasoconstrictor @ 1 mg/kg.b.wt.) comprised of 12 animals in each group.
In six animals from each group proximal paravertebral nerve block was
performed using conventional method and in other 6 animals using ultrasound guidance. Efficacy of these local anaesthetic were evaluated with reference to
clinico-physiological, haematological, biochemical parameters on 0, 1, 24 and
48 hours. Assessment of analgesia was carried out by recording onset of
action, duration of action, local (skin) temperature and area of desensitization.
The minimum duration of action was recorded in group 2 followed by group 1
and group 3 in both the methods. The longer duration of action was recorded
in group 3 followed by group 2 and group 1 in both method. There was a
highly significant difference in the onset and duration of action between all
groups (p<0.01), whereas the non-significant difference was recorded on
comparison between conventional and ultrasound guided nerve blocks. There
was statistically significant difference (P 0.01) in skin temperature before
and after proximal paravertebral nerve block in all the groups. The entire flank
area gets desensitized quickly in group 2 followed by group 1 and group 3.
The clinico-physiological parameter showed non significant and transcient
fluctuations which were within normal physiological limits. In haematological
parameters Hb and TLC decreased non-significantly at 1 hour interval, which
increased non significantly at 24 hours onwards. The PCV and TLC showed a
non significant increase from 1 hour onwards. Non significant increase in
neutrophil was observed from 1 hour onwards, whereas non significant
lymphocytopenia was recorded in all groups. Eosinophils, basophils and
monocyte showed non-significant fluctuations within normal physiological
limits and have no clinical relevance. The biochemical parameters like ALT,
AST BUN and creatinine showed a non significant (p>0.05) fluctuations.
Sodium and potassium values were varied non significantly and were within
normal physiological limits. In the light of research it can be concluded that
4% Articaine HCl has a rapid onset of analgesia as compared to other two
drugs whereas, 0.75% Ropivacaine HCl has longest duration of action. There
was non significant variation observed in proximal paravertebral nerve block
performed either by conventional method or by ultrasound guided technique.
However ultrasound guided proximal paravertebral nerve block in cattle is
feasible, effective and could reduce the complication associated with the
conventional method/blind technique.