Preparation of Recipient Wound Bed by Platelet Rich Plasma for Skin Flaps in Dogs
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Date
2020-03
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Abstract
location and site of the
wound. Subjective evaluation of wound healing based on the physical observations,
clinical photography, wound planimetry studies were evaluated. Additionally,
hematological, bacteriological, biochemical, and histopathological evaluation were done
for the recipient wound bed and skin flap. A subjective analysis of vascularity of the donor
site was performed through Colour flow Doppler ultrasonography. Platelet rich plasma had
the supreme advantage as it offered a multiple synergistically working growth factors that
promoted mitogenesis of mesenchymal cells at the wound site. Growth factors viz.,
transforming growth factor-b, platelet derived growth factor and vascular endothelial
growth factor were released after platelet degranulation led to fibroblast recruitment,
proliferation and matrix remodelling which ultimately leads to good granulation tissue
formation and wound healing in the cases.
Description
TNV_IJCMAS_2020_9(3)954-961