INTERACTION KINETICS OF ENROFLOXACIN WITH HYDRATED SODIUM CALCIUM ALUMINOSILICATE – A TOXIN BINDER IN BROILER CHICKEN AUTHORS
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Date
2015-05
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Abstract
The study was conducted to explore the influence of hydrated sodium
calcium aluminosilicate (HSCAS), a toxin binder commonly used in
poultry feed, on the pharmacokinetic behavior of enrofloxacin in
broiler chicken. Control group received normal feed free of toxin
binder whereas HSCAS group was supplemented with HSCAS @
0.5% in feed. Enrofloxacin was administered as single pulse dose
(@10mg.kg-1) through drinking water to both the groups. Blood
samples were collected at predetermined time intervals after drug
administration and plasma was separated and analyzed for enrofloxacin
concentrations using HPLC. Highly significant (p<0.01) decrease in
mean plasma concentration of enrofloxacin was noticed in HSCAS
Description
TNV_WJPR_2015_4(5)1867-1882
Keywords
Veterinary Science