Premature Centromere Division and Spontaneous Abortion
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Date
2013
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Abstract
Background: Premature Centromere Division (PCD) was observed in the chromosomes of metaphase spreads in a patient with the history of recurrent abortions. Case Report: Short term leukocyte cultures were set up with blood sample from the woman with a history of recurrent abortions for the past four consequent years. 25 % of the metaphase spreads screened displayed premature centromere division of the chromosomes in each of the cells. Conclusion: This abnormal behavior of the centromeres may predispose the individual to cell division errors due to chromosome instability and the consequences of which may be a spontaneous abortion.
Description
TNV_IJMTFM_2013_3(2)67-70
Keywords
Veterinary Science