IMMUNOMODULATORY EFFECT OF SUBLETHAL DOSE OF CITRININ AND AFLATOXIN IN BROILER CHICKEN
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Date
2016-05
Journal Title
Journal ISSN
Volume Title
Publisher
TANUVAS
Abstract
The present study was planned to find out the individual and combined
immunomodulatory effects of sublethal doses of citrinin (CTN) (5 ppm) and aflatoxin (AF)
(0.5 ppm) in broiler chicken. Ninety-six newly hatched broiler chicks were randomly allotted to 4 groups of 24 birds each and fed with control, CTN (5 ppm), AF (0.5 ppm) and CTN (5 ppm) + AF (0.5 ppm) diets from 0 to 6 weeks of age. The birds were vaccinated against Newcastle disease (ND) virus on 7"‘ and 28"’ day of age. The HI titres to ND vaccination and the stimulation index of splenocytes decreased significantly (P<0.05) in all the mycotoxin treated groups when compared to the control group. The present study indicated that CTN even at the sublethal dose level could lower the immune status of the birds and among the mycotoxin fed groups. AF played a more potential role in causing the reduction when compared to CTN.
Description
TNV_IJVASR_2016_45(3)621-625
Keywords
Veterinary Science