IN VITRO AND IN VIVO TRANSCRIPTIONAL CYTOKINE RESPONSES AGAINST DIFFERENT PATHOTYPES OF NEWCASTLE DISEASE VIRUSES
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Date
2015
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
TANUVAS, Chennai
Abstract
The focus of the present study is to generate data for evolving the molecular pathogenesis of
Newcastle disease in chickens using different pathotypcs (both virulent and less vírulent) of
Newcastle disease virus. The important objective is to determine the relative changes in the
expression of certain genes involved in inflammation, immunity and apoptosis against infection
with different pathotypes of NDV. For the in vilm study Chicken embryo fibroblasts and for in
vívo splenocytes from maternal antihody negative chickens were used. The lcntogcnic NDV
strain D58 and a viscerotropic velogenic isolate of NDV- Dl65 were used.
Description
TNV_TH_2015_MVM13033
Keywords
Veterinary Science, Veterinary Microbiology