Thumbnail Image

Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar

Browse

2012 - 201922020 - 20242
Reset filters
Author: Pradeep Kumar ×
Reset filters

Search Results

Now showing 1 - 4 of 4
  • Thumbnail Image
    ThesisItemRestricted
    Studies on etiology, haematobiochemical changes and therapeutics of diarrhoea in bovines
    (LUVAS,Hisar, 2023-04) Pradeep Kumar; Tarun Kumar
    Chronic diarrhoea is a significant problem in the livestock industry, leading to economic losses and requires veterinary attention. A study was conducted to understand the clinical features and hematological and biochemical changes in animals affected by chronic diarrhea. The study included detailed history of all affected animals, with an age range of 2 months to 14 years, and majority of affected animals (61.25%) were more than five years old in their third to fourth lactation (43.75%). The duration of illness ranged from 1 day to 1.5 years, and 61.25% of cases were chronic. Clinical signs included normal feed intake in 62.5% of animals, anorexia in 25%, and inappetence in 12.5%. Water intake was reduced in 83.75% of animals, and frequency of defecation ranged from 6-10 times daily in 57.5% of animals while more than 10 times daily was present in 27.5% of cases. Hematochezia and melena was found in 1.25% and 3.75% of cases, respectively. Milk production was reduced remarkably (more than 50%) in 60% of cases, causing great economic loss to the animal owners. Hematological findings showed anemia, lower hemoglobin, higher TLC, neutrophilia, and lymphopenia. Biochemical studies revealed hyponatremia, hypokalemia, hyperchloremia, hypocalcemia, hypophosphatemia, hypomagnesemia, increased activity of liver/skeletal enzymes, hypoglycemia, increased creatinine and BUN, hyperproteinemia, hypoalbuminemia, and hyperglobulinemia. These findings can aid in the diagnosis and management of chronic diarrhea in livestock. Etiological findings through highlighted the importance of locating the persistently infected animal as it will continue to spread infections to the healthy animals living in vicinity. Antibiotic sensitivity tests highlighted Amoxicillin/sulbactum as best drug. Therapeutic trial with same antibiotic further supplemented their outcome in combination with Lugol‘s Iodine. Diarrhoea as a disease condition caused by multiple etological agents.In present study occurence of BVDV as a reason for diarrhoea in bovines was reported as 2.50%, while Mycobacteruium paratuberculosis caused diarrhoea in 3.75% cases. Parasitic causes of diarrhoea were reported as 11.25%. This study highlights the significance of clinical, hematobiochemical and etiological factors associated with chronic diarrhoea.
  • Thumbnail Image
    ThesisItemRestricted
    Studies on etiology, haematobiochemical changes and therapeutics of diarrhoea in bovines
    (Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar, 2024-04) Pradeep Kumar; Tarun Kumar
    Hematochezia, haematological, antibiotic sensitivity, amoxicillin, persistently infected, Lugol‘s Iodine Chronic diarrhoea is a significant problem in the livestock industry, leading to economic losses and requires veterinary attention. A study was conducted to understand the clinical features and hematological and biochemical changes in animals affected by chronic diarrhea. The study included detailed history of all affected animals, with an age range of 2 months to 14 years, and majority of affected animals (61.25%) were more than five years old in their third to fourth lactation (43.75%). The duration of illness ranged from 1 day to 1.5 years, and 61.25% of cases were chronic. Clinical signs included normal feed intake in 62.5% of animals, anorexia in 25%, and inappetence in 12.5%. Water intake was reduced in 83.75% of animals, and frequency of defecation ranged from 6-10 times daily in 57.5% of animals while more than 10 times daily was present in 27.5% of cases. Hematochezia and melena was found in 1.25% and 3.75% of cases, respectively. Milk production was reduced remarkably (more than 50%) in 60% of cases, causing great economic loss to the animal owners. Hematological findings showed anemia, lower hemoglobin, higher TLC, neutrophilia, and lymphopenia. Biochemical studies revealed hyponatremia, hypokalemia, hyperchloremia, hypocalcemia, hypophosphatemia, hypomagnesemia, increased activity of liver/skeletal enzymes, hypoglycemia, increased creatinine and BUN, hyperproteinemia, hypoalbuminemia, and hyperglobulinemia. These findings can aid in the diagnosis and management of chronic diarrhea in livestock. Etiological findings through highlighted the importance of locating the persistently infected animal as it will continue to spread infections to the healthy animals living in vicinity. Antibiotic sensitivity tests highlighted Amoxicillin/sulbactum as best drug. Therapeutic trial with same antibiotic further supplemented their outcome in combination with Lugol‘s Iodine. Diarrhoea as a disease condition caused by multiple etological agents.In present study occurence of BVDV as a reason for diarrhoea in bovines was reported as 2.50%, while Mycobacteruium paratuberculosis caused diarrhoea in 3.75% cases. Parasitic causes of diarrhoea were reported as 11.25%. This study highlights the significance of clinical, hematobiochemical and etiological factors associated with chronic diarrhoea.
  • Thumbnail Image
    ThesisItemRestricted
    Clinico-biochemical and therapeutic investigation on hepatic insufficiency in goats
    (LUVAS, 2012) Pradeep Kumar; Sridhar
    The investigation was undertaken on twelve clinical cases of hepatic insufficiency in goats brought to Teaching Veterinary Clinical Complex (TVCC), LLRUVAS, Hisar as well as from Hisar city and adjoingin areas. Six apparently healthy goats from same areas were kept as controls. These animals were subjected to clininico-haemato-biochemical, ultrasonographic and therapeutic investigations Clinical manifestations of the condition in diseased goats included one or a combination of non-specific signs like acute or chronic anorexia, weakness, vague digestive disturbances, progressive emaciation, weakness, diarrohoea, pale mucous membranes, melena, depression, oedema of dependent parts, photosensitization, rarely oedema of the submaxillary space. Significantly lower value of haemoglobin was observed in diseased goats as compared to healthy control animals probably due to haepatocellular changes. Slight leukocytosis was also observed probably as a result of endotoxaemia which is common in liver disease. Significantly higher activities of enzymes viz. serum aspartate amino transferase, serum alkaline phosphatase, and serum gamma glutamyl transferase and sorbitol dehydrogenase were seen in diseased animals indicating hepatic insufficiency. Significantly lower serum total proteins and albumin in diseased animals were also indicative of hepatic dysfunction which was also evident from a significant elevation of serum total bilirubin. Malondialdehyde, an indicator of lipid peroxidation in oxidative stress, was also found to be signifacantly higher in diseasesd goats. . Ultrasonographic studies revealed focal and diffused hepatitis alongwith evidence of cirrhosis and ascites on the basis of changes in echogenicity as well as other structural abnormalities. Results of therapeutic trial in two groups of six animals each revealed a better response to therapy with Picrorrhiza kurroa (Kutki), Eclipta alba (Bhringraj) alongwith ascorbic acid (an antioxidant) as compared to same drug combination without ascorbic acid.
  • Thumbnail Image
    ThesisItemRestricted
    Comparison of different diagnostic tests for trypanosoma evansi infection in buffaloes
    (LUVAS, 2016) Pradeep Kumar; Vohra, Sukhdeeep
    For the screening of Trypanosoma evansi in buffaloes in and around Hisar, a total of 400 blood samples (300 healthy and 100 suspected cases) were collected from 7 blocks of Hisar district. Out of total blood samples examined, none of samples were found positive by parasitological methods viz. wet blood film, microhaematocrit technique and thin blood smear by giemsa staining. Screening of sera from these samples by mAb-LAT indicated 95(23.7%), 101(25.2%), 84(21.0%), 38 (9.5%) and 82 (20.5%)samples as strong,moderate,weak,suspected and negative, respectively. mAb-LAT showed highest prevalence in females and animals above 8 years of age. mAb-LAT positive samples had lower values of Hb and PCV while higher body temperature mAb-LAT positive blood samples when inoculated in mice gave negative results on 3rd,5th, 7th and 14th day post-inoculation.