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Govind Ballabh Pant University of Agriculture and Technology, Pantnagar

After independence, development of the rural sector was considered the primary concern of the Government of India. In 1949, with the appointment of the Radhakrishnan University Education Commission, imparting of agricultural education through the setting up of rural universities became the focal point. Later, in 1954 an Indo-American team led by Dr. K.R. Damle, the Vice-President of ICAR, was constituted that arrived at the idea of establishing a Rural University on the land-grant pattern of USA. As a consequence a contract between the Government of India, the Technical Cooperation Mission and some land-grant universities of USA, was signed to promote agricultural education in the country. The US universities included the universities of Tennessee, the Ohio State University, the Kansas State University, The University of Illinois, the Pennsylvania State University and the University of Missouri. The task of assisting Uttar Pradesh in establishing an agricultural university was assigned to the University of Illinois which signed a contract in 1959 to establish an agricultural University in the State. Dean, H.W. Hannah, of the University of Illinois prepared a blueprint for a Rural University to be set up at the Tarai State Farm in the district Nainital, UP. In the initial stage the University of Illinois also offered the services of its scientists and teachers. Thus, in 1960, the first agricultural university of India, UP Agricultural University, came into being by an Act of legislation, UP Act XI-V of 1958. The Act was later amended under UP Universities Re-enactment and Amendment Act 1972 and the University was rechristened as Govind Ballabh Pant University of Agriculture and Technology keeping in view the contributions of Pt. Govind Ballabh Pant, the then Chief Minister of UP. The University was dedicated to the Nation by the first Prime Minister of India Pt Jawaharlal Nehru on 17 November 1960. The G.B. Pant University is a symbol of successful partnership between India and the United States. The establishment of this university brought about a revolution in agricultural education, research and extension. It paved the way for setting up of 31 other agricultural universities in the country.

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  • ThesisItemOpen Access
    Studies on immune status of indigenous and exotic breeds of domestic fowl
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-08) Yadav, Renuka; Rajesh Kumar
    Present study was carried out for comparative evaluation of some indigenous and exotic breeds of domestic chicken with regard to the innate immune response, adaptive immune response and resistence to infection following challenge with infectious agent. One exotic (RIR) and two indigenous breeds (Kadaknath, Uttara fowl) were used for study. All the birds were reared in deep litter system with ad-libtum feed and water throughout the experiment. The experiment lasted for 60 days. Significant difference was observed among parameters studied viz; mean total leukocyte count, differential leukocyte count, leukocrit, serum globulin, A/G ratio, phagocytic activity and opsonocytophagic index, among various breeds of chicken at all stages and all the innate and adaptive immune parameter was significantly higher in RIR compared to Kadaknath and Uttara fowl breed of chicken. The RIR showed highest hemagglutination inhibition titre following NDV immunization till the end of the experimental period followed by Kadaknath and Uttara fowl. Cell mediated immune (CMI) response was also observed to be higher for RIR breed compared to Kadaknath and Uttara fowl. The lymphocyte stimulation index was highest in RIR and the lowest in Uttara fowl. Maximum mortality was observed in Uttara fowl up to 15 days post challenge with a virulent virus and antibody titre was maximum in RIR breed at 3 and 7 days post challenge but at 14 days post challenge kadaknath showed highest antibody titre.
  • ThesisItemOpen Access
    Evaluation of haemato-biochemical profile and anti-osteoporotic potential of Moringa oleifera in rats
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-03) Rawat, Parul; Ahmed, A.H.
    The present study was carried out to evaluate haemato-biochemical profile and antiosteoporotic potential of Moringa oleifera in combination with prednisolone induced osteopororsis in rats. Osteopororsis was induced in rats by administration of prednisolone @ 1mg/ kg, bwt, I.P, daily for 28 days under aseptic conditions. Rats were divided in 6 groups of six animals each. Group I served as control, group II and group III were administered aqueous extract of Moringa oleifera (MOAE) @ 200mg/kg b. wt and 500mg/kg b.wt repectively. In group IV and V aqueous extract of Moringa oleifera (MOAE) @ 200mg/kg b. wt and 500mg/kg b.wt with prednisolone @ 1mg/kg b wt and in group VI prednisolone was administered @ 1mg/kg b wt. daily for 28 days. The antiosteoporotic potential was measured by determining bone histomorphometry by X-ray radiography of femur of rats. Osteoporotic biomarkers were recorded by determining alkaline phosphatase and serum calcium. Osteoporotic biomarkers such as ALP and calcium were reduced after treatment with prednisolone. Effect on hepatorenal function was assessed by determining effect on AST, creatinine and BUN level in serum. Treatment with MOAE-1 and MOAE-2 with prednisolone treated rats restored the blood urea nitrogen level and creatinine level. There was signinficant (P<0.05) alteration in body weight, femur weight and radiographic examination which indicated the induction of osteoporosis after 28 days in rats.. In groups treated with MOAE-1 and MOAE-2 with prednisolone showed improvement in level of calcium as compared to control after 14th and 28th day of treatment. In prednisolone treated group dislocation of femur head from pelvic girdle and fracture in mid shaft of femur were observed , which conforms osteoporosis in prednisolone treated group. osteoporosis very often manifests as a bone fracture. Femoral fractures are the most feared complication of osteoporosis. Prednisolone altered hematological parameters like Hb, PCV, TLC, TEC and DLC , effect was ameliorated by treatment with aqueous extract of Moringa oleifera @ 200 and 500 mg/kg b.wt for 28 days. Histopathological changes in liver, kidney and spleen were observed in prednisolone treated groups , and groups including prednisolone with MOAE-1 and MOAE-2. Thus, it can be concluded from present study that the aqueous extract of Moringa oleifera has antiosteoporortic potential against prednisolone induced osteoporosis
  • ThesisItemOpen Access
    Studies on epidemiology, isolation and molecular analysis of fowl adenoviruses from the domestic chicken with respiratory disease conditions
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-08) Bisht, Ritika; Rajesh Kumar
    Fowl adenoviruses (FAdV) are the ubiquitous and cause extensive damage to the poultry industry. They are known to be associated with various disease conditions such as Inclusion body hepatitis, Hydropericardium Syndrome, respiratory disease, tenosynovitis, impaired growth, reduced egg production, aplastic anemia, atrophy of bursa and thymus, enteritis and conjunctivitis in chickens and other birds. Present study was undertaken to study epidemiology, to isolate and perform molecular analysis of fowl adenoviruses from the chickens with the respiratory disease conditions. Natural outbreaks investigated during the study revealed 2 –15% mortality among the affected birds aged 3-6 weeks. General postmortem findings were enlarged and friable liver with necrotic foci, enlargement of kidney, congestion and haemorrhagic trachea, congested lungs. Four isolates of fowl adenoviruses were propagated in primary CEL cell culture. The cytopathic effects were characterized by rounding of the cells, degeneration, increase in the refractive index of the cells and microplaques formation. AGPT, CIEP, IFAT, Dot-ELISA and Sandwich ELISA determined the presence of the virus in infected tissues and cell culture. Intensely basophilic intra nuclear inclusion bodies were also visualized following MGG staining of CEL cells. The genomic DNAs were extracted from the infected CEL cells and PCR was carried out for amplification of L1 region of the hexon gene showing amplicons of the ~900 bp. On digestion with MluI, three isolates were digested and the two bands of 400 and 500 bp were visualized and with the enzyme StyI, only one isolate was digested and two bands of 480 and 420 bp were obtained. None of the isolates were digested by the enzymes BglI, BsiWiI and ScaI. RE analysis revealed that isolates belong to two serotypes 5 (R-66) and 8 (R-53, R-43, R-63). Thus, it can be concluded that these serotypes are involved in respiratory disease of domestic chickens in India.
  • ThesisItemOpen Access
    Clinico-haematobiochemical alterations and therapeutic management of canine parvovirus infection with special reference to alternative therapy
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-07) Pant, Kirti; Shukla, S.K.
    The present study was conducted with the aim to calculate the prevalence of Canine Parvoviral infection in and around Pantnagar along with its therapeutic management via fortification of alternative medicines to achieve better results. A total of 72 cases of gastroenteritis were reported in Teaching Veterinary and Clinical Complex, Pantnagar from December 2018 to May 2019. Out of these, 48 cases were found positive for Canine Parvoviral infection showing an overall prevalence of 66.66%. Confirmation of positive cases was done based on observed clinical signs and Rapid Parvovirus Antigen Detection Kit. Total six groups of 36 dogs were made for the study. Group I comprised of healthy dogs with no infection. Thirty dogs found positive for Canine Parvoviral infection were divided in 5 groups I, II, III, IV, V comprising of six dogs each. Group II comprised of infected dogs which were treated symptomatically. Group III comprised of infected dogs which were given Astragalus along with symptomatic therapy orally @ 1-2 ml bid for 5 days. Group IV comprised of infected dogs which were given Arsenicum album (30C) orally @ 1-2 drops bid for 5 days along with symptomatic therapy. Group V comprised of infected dogs which were given Mercurius corrosivus (30C) orally @ 1-2 drops bid for 5 days along with symptomatic therapy. Group VI comprised of infected dogs which were given Zingiber (3X) orally @ 1-2 drops bid for 5 days along with symptomatic therapy. Maximum affected cases were in males ranging about 62.5% of age group 0-3 months (43.75%) having body weight < 5 kg (45.83%). Maximum (75%) cases were seen in the month of February and April followed by March (68.75%), December (66.66%), January (62.5%) and least in May (50%). Breed wise maximum prevalence was seen in non-descript or mixed breed (39.58%) followed by Labrador (16.66%), Rotweiler (12.5%), Bhutia and German Shephard (10.42%), Spitz and Mastiff (4.16%) and least in Pitbull (2.08%). Total 75% pups which were not vaccinated against canine parvoviral infection were found prone to infection as compared to those which were vaccinated (25%). Most common clinical signs observed were anorexia (89.58%), vomition (87.5%), bloody diarrhea (79.16%), dehydration (50%), sub-normal rectal temperature (62.5%), pale conjunctival mucous membrane (58.33%) and reduced body weight (45.83%). Haematological parameters like haemoglobin, total leukocyte count and lymphocyte percentage showed significant increase (P < 0.05) in all groups with maximum increase in group VI on day 5 post – treatment. Biochemical parameters like total protein, albumin, globulin also improved significantly (P < 0.05) in all groups V and VI on day 5 post – treatment. AST, ALT (P< 0.05) and ALP (P < 0.05) values which were increased on day ‘0’, decreased significantly after treatment in group III and VI. Group II showed similar results but mean values of all haematological and biochemical parameters of dogs from group II were less significantly changed as compared to other groups. Mean values of these parameters in dogs from group I remained within normal physiological limit during study period. Better results were seen in Group VI followed by Group IV, Group V, Group III and Group II, respectively.
  • ThesisItemOpen Access
    Studies on incorporation of Ashwagandha (Withania somnifera) on quality characteristics of shrikhand
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-06) Pal, Manisha; Singh, P.K.
    Shrikhand is an Indian dessert which is made by fermentation of milk by using known strain of lactic acid bacteria. It is a semi soft, sweetish sour, whole milk product developed from fermented curd (dahi). Now a days functional foods are prepared by adding active component that fulfill the basic nutritional requirement and also provides an additional physiological benefits in the population. For designing nutraceutical food herbal extract having active component could be incorporated in the dairy products. Among the fermented dairy product one of the most acceptable product is shrikhand in which herbal extract can be added. Ashwagandha (Withania somnifera) powder was added in different proportion to develop a herbal shrikhand. So, present investigation is designed to evaluate the quality characteristics and storage stability of ashwagandha powder in different proportion viz. 0.2%, 0.4% and 0.6% with 40% cane sugar (by weight of chakka) to prepared shrikhand. For storage stability, samples were stored at 5±1ºC for 15 days and pH, titrable acidity, antioxidant property, sensory attributes and microbilogical examination were evaluated at regular interval. Proximate analysis revealed a non significant (P>0.05) difference among all the treatments. Comparison of pH and titrable acidity revealed that addition of ashwagndha powder in shrikhand decreases the pH (P<0.05) significantly whereas tritable acidity was increased (P<0.05) significantly. TBARS and FFA value of T3 group was lowest (P<0.05) than other groups. Texture profile analysis showed higher (P<0.05) firmness and consistency of control shrikhand whereas higher (P<0.05) cohesiveness and index of viscosity was observed in T3 group. Sensory score was significantly (P<0.05) higher for color, flavour and overall acceptability in T1 group whereas higher (P<0.05) texture score was found in T1. Microbiological analysis revealed that TPC, Yeast and Mold were significantly (P<0.05) lower in T3, followed by T2, T1 and C. Hence, based on the following results, we can conclude that T1 (0.2% ashwagandha powder added shrikhand) has better sensory score than C, T2 and T3. While T3 has potential antioxidant, antimicrobial property than C, T1, T2.
  • ThesisItemOpen Access
    Effect of soy fiber incorporation on physico-chemical, microbiological and sensory attributes of low-fat paneer
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-06) Bisht, Arti; Singh, P.K.
    Paneer is an important indigenous wholesome dairy product that is extensively used as a base material in the preparation of a large number of Indian culinary dishes. It is a rich source of good quality protein, fat, vitamins and minerals but also contributes to a substantial fat intake in the diet. As consumers are becoming more health conscious, so there is a need to develop low fat diet that not only contains fewer amounts of fat but also give good taste to the consumers. The objectives of the present study was to develop a low-fat paneer, optimization of the type and amount of soy fiber in low fat paneer, evaluation of physico-chemical, sensory and microbiological properties of low fat paneer enriched with soy fiber and to study the storage stability of soy fiber enriched low fat paneer. Optimization of soy fiber level was carried out (0.1 to 1.5%) and Response Surface Methodology (RSM) was used for designing of the experiment (based on sensory scores) as well as to select the appropriate level of the soy fiber. Three trials of the experiment were done and each sample was evaluated in duplicates and data obtained was analyzed statistically by using analysis of variance (ANOVA) technique. Sensory evaluation of paneer was carried out by using 8 point Descriptive Scale. The proximate composition(moisture, protein, fat, ash and total solids) of control as well as treated samples were determined by AOAC (2005) method and it was found that there was non-significant(P>0.05)difference between control and treatment groups. The highest average score for overall acceptability of low-fat paneer was recorded in T2 (7.21) followed by T1(6.75), T0(6.20) and T3(6.13). Among all the combinations of soy-fiber in low-fat paneer the best one in terms of flavor, colour & appearance, body & texture, mouthfeel and overall acceptability was paneer having 0.4% soy fiber. On the basis of Texture Profile Analysis it was found that on addition of soy fiber, hardness as well as chewiness of low fat paneer decreases significantly (P<0.05) as compared to control. In case of microbiological analysis, T3 sample had higher TPC and Yeast & Mold Count as compared to other samples and there was significant (P<0.05) increase in the TPC and Yeast & Mold count on storage. Thus, on the basis of following results, we can conclude that the quality of low-fat paneer having 0.4% soy fiber was similar to the paneer made from milk having 6% fat and 8.5% SNF. This paneer was found to have higher protein content and low fat content as compared to the paneer made from buffalo milk (6% fat) and thus it can be therefore, useful from therapeutic point of view for all consumers suffering from cardiovascular diseases.
  • ThesisItemOpen Access
    Isolation and propagation of muscle-derived mesenchymal cells and assessment of their regenerative potential in skeletal muscle injuries in mice
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-08) Godiyal, Akanksha; Kandpal, Manjul
    The present study was conducted on 24 clinically healthy Swiss albino mice (8-10 weeks old) of either sex, weighing 25-35 gm. The animals were divided into three groups viz. group A, B and C, having 8 animals in each. In all the groups, the gastrocnemius muscle was injured by surgical resection of the muscle. After creating muscle injury, PBS was injected in the mice of group A (control group) on day 1 and 5. In the mice of group B, MDSCs were injected in the injured muscle on day 1 and 5. While in the mice of group C, MDSCs were injected in the injured muscle on day 5 and 10. Muscle-derived mesenchymal cells were isolated by modified preplate method and cultured in proliferation media and incubated at 37 °C in a humidified 5% CO2 incubator. When the cells reached 70-80 % confluency, they were harvested using 0.25% trypsin-EDTA and cells were implanted at the site of injury in animals of group B and C. The regenerative potential of MDSCs for repair of the injured muscle was assessed by the evaluation of physical parameters, physiological parameters, wound condition, biochemical parameters, histopathological studies and free wire hanging test at different time intervals. Also, gene expression profiling of mVEGF was done for the evaluation of muscle regeneration via angiogenesis on day 7 and 15 after creation of muscle injury wound. On the basis of parameters observed in the present study, early and better healing of injured muscle was revealed in the mice of group B. There was early reduction in swelling, exudation, warmth and pain at the repaired site in the mice of group B. The level of enzymes CK, LDH, AST and AST was decreased significantly in the mice of group B. Also, the score of free wire hanging test was highest in the mice of group B as compared to the mice of group A and C indicating complete regeneration of the injured muscle. Histopathological observations revealed the presence of well organized, polygonal shaped regenerated myofibers having peripherally arranged nucleus in the mice of group B. Gene expression analysis showed upregulation of the gene mVEGF in group B as compared to control group. Results concluded that muscle-derived mesenchymal cells can be isolated by modified preplate method, cultured in-vitro and could be used without any scaffold for regeneration of injured skeletal muscle. Therefore, the current study confirmed that muscle-derived mesenchymal cells may be used for early, better and complete muscle regeneration in clinical cases of muscle injuries.
  • ThesisItemOpen Access
    Studies on the chemotherapeutic effects of Docetaxel and gene expression during regression of mammary tumour in canine
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-08) Upadhyay, Prachi; Jadon, N.S.
    Sixteen adult dogs suffering from canine mammary tumours used in this study were divided randomly into two groups having equal number of dogs (Group I and Group II). Patients of group I were subjected to administration of docetaxel (@30mg/m2 weekly four consecutive cycles) and patients of Group II were subjected to surgical excision of tumoral growth followed by chemotherapy with docetaxel (@30mg/m2 weekly four consecutive cycles). The therapeutic efficacy was determined by observing various parameters clinical (physical appearance and gross regression), radiological assessment, ultrasonographic screening, haematological (haemoglobin, total erythrocyte count, total leucocyte count and differential leucocyte count), biochemical (aspartate amino transferase, alanine amino transferase, serum creatinine and serum urea nitrogen) histopathological and gene expression profiling of EGFR to assess the fold change in its expression as result of treatment modality via RT-PCR analysis. The rectal temperature, heart rate and respiration rate showed non-significant changes at various time intervals in both the groups. Haemoglobin levels decreased non-significantly, total erythrocyte count and platelets varied non-significantly in both the groups. Neutrophil count revealed significant decrease in both the groups, whereas significant increase in lymphocyte increased significantly in both the groups and significant increase was observed in group II as compared to group I. Biochemical study revealed significant increase in levels of AST, BUN and serum creatinine within group II further, significant increase was also observed in group II as compared to group I. istopathologically, five (31.25%) tumours appeared to be benign while eleven (68.75%) tumours were malignant. On ultrasonographical study, no difference in regularity of tumour shape and margins, echotexture and shadowing was observed among benign and malignant tumours, tumour echogenicity was homogenous in benign tumours and posterior enhancement was evident in malignant ones. Lateral and ventrodorsal radiographs manifested lung metastsis in 10 cases however, three cases out of eight in group I and one case out of eight in group II revealed slight lung clearence on day 28. Clinical response rate was responders 62.5% and non-responders 37.5% in group I. In group II, complete response with no reoccurrence was observed in five cases (62.5%) and three cases showed reoccurrence, these patients had a tendency towards better survival rates and prolongation of life as compared to group I. Gene expression profiling revealed that EGFR receptor was comparatively more down-regulated in patients of group II subjected to surgical resection of canine mammary tumours followed by chemotherapy as compared to patients of group I which were subjected to docetaxel therapy. On the basis of above mentioned parameters it was concluded that the combination therapy had better response rate, survival rates and more down-regulation of EGFR gene involved in tumour invasion and metastasis. Combination of surgery and chemotherapy with docetaxel may be used safely by field veterinarians under proper observation for the treatment of mammary tumours in canines.
  • ThesisItemOpen Access
    Effect of dietary incorporation of varying combination of black cumin (Nigella sativa) seed and ginger (Zingiber officinale) rhizome powder as feed additive on performance of commercial broiler chickens
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-08) Sharma, Vandana; Tiwari, D.P.
    A feeding trial was conducted to discern the effect of dietary incorporation of black cumin (Nigella sativa) seed and ginger (Zingiber officinale) rhizome powder in varying proportions on growth performance, nutrient utilization, carcass traits, haemato-biochemical parameters, sensory evaluation of meat and economics of commercial broiler chickens production. A total of 120, day-old broiler chicks were divided randomly into 4 treatment groups with 3 replicates each i.e. 10 broiler chicks per replicate. Chicks of treatment T1 (control) were fed basal diet (starter and finisher), whereas in treatment groups T2, T3 and T4, basal diet was incorporated with 0.25% black cumin seed + 0.75% ginger rhizome powder, 0.50% black cumin seed + 0.50% ginger rhizome powder, 0.75 % black cumin seed + 0.25% ginger rhizome powder, respectively, as feed additive. The feeding trial lasted for 42 days viz., 0-21 days (starter phase) and 21-42 days (finisher phase). A metabolism trial was conducted during the 6th week of feeding trial to know the nutrient utilization. On the 42nd day of the feeding trial two birds from each treatment were slaughtered and samples of breast and thigh muscle were collected for sensory and proximate analysis. Blood samples were also collected on the same day for haemato-biochemical parameters. During the starter phase (0-21 days), maximum weight gain was recorded in broiler chicks of treatment group T4 fed diet incorporated with 0.75 % black cumin seed + 0.25% ginger rhizome powder and significantly higher than T1 followed by treatment groups T2 and T3. Performance index was significantly higher in treatment group T4 followed by T2, T3 and T1, respectively. During finisher phase (21-42 days), average body weight gain differ significantly among different groups. Maximum weight gain was recorded in broiler chicks of treatment group T1 fed with control diet, followed by treatment groups T2, T3 and T4. The average cumulative weight gain was 1463.30g, 1470.00g, 1412.20g, 1389.70g in broiler chicks of treatment group T1, T2, T3, T4, respectively and did not differ significantly. There was no improved growth performance in terms of body weight gain, feed conversion ratio and performance index due to dietary incorporation of black cumin seed and ginger rhizome powder. Incorporation of black cumin seed and ginger rhizome powder in the diet of broiler chickens did not affect nutrient utilization in terms of dry matter, organic matter, ether extract and crude protein metabolizability. The various carcass traits in broiler chicks were not affected due to dietary incorporation of combination of black cumin seed and ginger rhizome powder. There was significant differences in protein and ether extract content of thigh muscles, whereas these parameters were statistically similar in breast muscles. There was significant increase in protein content and decrease in ether extract contents of thigh muscles. Maximum crude protein content was found in treatment group T4, followed by treatment groups T3,T2 and T1, respectively. Minimum ether extract content was found in treatment group T2 and maximum in control group. All the values of hematological parameters were in normal range in broiler chicks of different treatment groups, without any significant effect. There was significant (P<0.05) reduction in serum cholesterol, triglycerides content and increase in serum total protein and albumin was observed for treatment group T4 fed on diet incorporated with 0.75% black cumin + 0.25% ginger rhizome powder, as compared to control group T1. Serum cholestrol was found minimum in treatment group T4(118.7 mg/dl) as compared to control group T1(136.73 mg/dl). Serum triglyceride content was also found minimum in treatment group T4 (51.29 mg/dl) as compared to control group T1 (60.20 mg/dl). Maximum serum total protein concentration was found in treatment group T4, followed by T3,T1 and T2, respectively. Maximum serum albumin concentration was found in group T4, followed by T3,T2 and T1, respectively. Serum globulin, glucose concentrations as well as serum ALP, ALT and AST activities was not affected due to dietary incorporation of black cumin seed and ginger rhizome powder. Sensory evaluation attributes were not significant among the different treatment groups. From the feeding trial, it is not economically viable to invest in different treatment diets, as compared to control diet. It is concluded that incorporation of combination of 0.75 % black cumin seed + 0.25% ginger rhizome powder in the diet of broiler chicks reduces serum cholesterol, triglycerides content and increase in serum total protein and albumin coupled with reduction in fat and increase in protein content of thigh muscles could be exploited for designer meat production.