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Govind Ballabh Pant University of Agriculture and Technology, Pantnagar

After independence, development of the rural sector was considered the primary concern of the Government of India. In 1949, with the appointment of the Radhakrishnan University Education Commission, imparting of agricultural education through the setting up of rural universities became the focal point. Later, in 1954 an Indo-American team led by Dr. K.R. Damle, the Vice-President of ICAR, was constituted that arrived at the idea of establishing a Rural University on the land-grant pattern of USA. As a consequence a contract between the Government of India, the Technical Cooperation Mission and some land-grant universities of USA, was signed to promote agricultural education in the country. The US universities included the universities of Tennessee, the Ohio State University, the Kansas State University, The University of Illinois, the Pennsylvania State University and the University of Missouri. The task of assisting Uttar Pradesh in establishing an agricultural university was assigned to the University of Illinois which signed a contract in 1959 to establish an agricultural University in the State. Dean, H.W. Hannah, of the University of Illinois prepared a blueprint for a Rural University to be set up at the Tarai State Farm in the district Nainital, UP. In the initial stage the University of Illinois also offered the services of its scientists and teachers. Thus, in 1960, the first agricultural university of India, UP Agricultural University, came into being by an Act of legislation, UP Act XI-V of 1958. The Act was later amended under UP Universities Re-enactment and Amendment Act 1972 and the University was rechristened as Govind Ballabh Pant University of Agriculture and Technology keeping in view the contributions of Pt. Govind Ballabh Pant, the then Chief Minister of UP. The University was dedicated to the Nation by the first Prime Minister of India Pt Jawaharlal Nehru on 17 November 1960. The G.B. Pant University is a symbol of successful partnership between India and the United States. The establishment of this university brought about a revolution in agricultural education, research and extension. It paved the way for setting up of 31 other agricultural universities in the country.

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  • ThesisItemOpen Access
    Clinico-haematobiochemical alterations and therapeutic management of canine parvovirus infection with special reference to alternative therapy
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-07) Pant, Kirti; Shukla, S.K.
    The present study was conducted with the aim to calculate the prevalence of Canine Parvoviral infection in and around Pantnagar along with its therapeutic management via fortification of alternative medicines to achieve better results. A total of 72 cases of gastroenteritis were reported in Teaching Veterinary and Clinical Complex, Pantnagar from December 2018 to May 2019. Out of these, 48 cases were found positive for Canine Parvoviral infection showing an overall prevalence of 66.66%. Confirmation of positive cases was done based on observed clinical signs and Rapid Parvovirus Antigen Detection Kit. Total six groups of 36 dogs were made for the study. Group I comprised of healthy dogs with no infection. Thirty dogs found positive for Canine Parvoviral infection were divided in 5 groups I, II, III, IV, V comprising of six dogs each. Group II comprised of infected dogs which were treated symptomatically. Group III comprised of infected dogs which were given Astragalus along with symptomatic therapy orally @ 1-2 ml bid for 5 days. Group IV comprised of infected dogs which were given Arsenicum album (30C) orally @ 1-2 drops bid for 5 days along with symptomatic therapy. Group V comprised of infected dogs which were given Mercurius corrosivus (30C) orally @ 1-2 drops bid for 5 days along with symptomatic therapy. Group VI comprised of infected dogs which were given Zingiber (3X) orally @ 1-2 drops bid for 5 days along with symptomatic therapy. Maximum affected cases were in males ranging about 62.5% of age group 0-3 months (43.75%) having body weight < 5 kg (45.83%). Maximum (75%) cases were seen in the month of February and April followed by March (68.75%), December (66.66%), January (62.5%) and least in May (50%). Breed wise maximum prevalence was seen in non-descript or mixed breed (39.58%) followed by Labrador (16.66%), Rotweiler (12.5%), Bhutia and German Shephard (10.42%), Spitz and Mastiff (4.16%) and least in Pitbull (2.08%). Total 75% pups which were not vaccinated against canine parvoviral infection were found prone to infection as compared to those which were vaccinated (25%). Most common clinical signs observed were anorexia (89.58%), vomition (87.5%), bloody diarrhea (79.16%), dehydration (50%), sub-normal rectal temperature (62.5%), pale conjunctival mucous membrane (58.33%) and reduced body weight (45.83%). Haematological parameters like haemoglobin, total leukocyte count and lymphocyte percentage showed significant increase (P < 0.05) in all groups with maximum increase in group VI on day 5 post – treatment. Biochemical parameters like total protein, albumin, globulin also improved significantly (P < 0.05) in all groups V and VI on day 5 post – treatment. AST, ALT (P< 0.05) and ALP (P < 0.05) values which were increased on day ‘0’, decreased significantly after treatment in group III and VI. Group II showed similar results but mean values of all haematological and biochemical parameters of dogs from group II were less significantly changed as compared to other groups. Mean values of these parameters in dogs from group I remained within normal physiological limit during study period. Better results were seen in Group VI followed by Group IV, Group V, Group III and Group II, respectively.
  • ThesisItemOpen Access
    Clinico-therapeutic studies on canine mycotic dermatitis
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-07) Joshi, Preeti; Prasad, Amit
    The.present work was undertaken to record the prevalence of canine dermatological disorders at Veterinary hospitals of Udham Singh Nagar and Nainital districts of Uttarakhand including Teaching Veterinary Clinical Complex, Pantnagar from (May, 2018-April, 2019) with special reference to mycotic dermatitis. Clinico-therapeutic trials were also carried out at TVCC, Pantnagar to evaluate the therapeutic efficacy of standard formulations viz. Terbinafine, Itraconazole and Griseofulvin with sunflower oil in group of dogs affected with mycotic dermatitis. A group of six healthy dogs were also included for comparison of results. Prevalence of various dermatological disorders were recorded,out of 12,556 dogs; 3929 dogs were suffering from various dermatological disorders recording an overall prevalence of 31.29%. Highest prevalence was found at Haldwani (53.66%) followed by Shantipuri (49.09%), Kicchha (38.67%), Kashipur (28.39%), Lalkuan (26.66%), Gadarpur (22.65%), Rudrapur (20.55%), Pratappur (14.47%) and Bajpur (17.56%) and lowest at Pantnagar (10.43%). At Pantnagar, dermatoses were recorded in 239 out of 2291 dogs comprising of 97 (40.58%) fungal, 66 (27.61%) tick/flea/lice infestation, 45 (18.82%) mange, 31 (12.97%) miscellaneous infection. In Pantnagar maximum cases were recorded in August (15.46%) followed by July (14.43%). In general, a higher percentage of dermatoses, was found in males with no age limit. It was observed that maximum cases of dermatological findings were recorded in mongrel dogs (32.63%) followed by German Shepherd (19.66%), Labrador (18.82%), other breeds (15.06%), toy breeds (13.80%). Microscopic and cultural examination of skin scrapings remarked maximum fungal affections were caused by Microsporum spp. (42.26%), Trichophyton spp. (24.74%), and Malassezia spp. (32.98%). Estimation of hemato-biochemical profiles revealed leucocytosis and increase in ESR in all dermatological cases. Average values of Hb, PCV, and TEC were significantly lower in fungal dermatological conditions when compared to control, while neutropenia and eosinophilia were evident in cases of fungal infection. Monocytes were significantly decreased in affected animals as compared to the healthy control. Significant increase in total protein and globulin and decrease in serum albumin, A/G ratio in dogs affected with mycotic dermatitis. Thirty six out of 97 dogs were randomly divided into 3 groups (n=6) for therapeutic evaluation of standard formulationsviz. Terbinafine, Itraconazole, Griseofulvin with sunflower oil. The clinical examination at an interval of 7 days for 21 days treatment was performed. Terbinafine was found superior to Itraconazole followed by Griseofulvin with sunflower oil in mycotic dermatitis. On the basis of the results of the present study, selected therapeutic regimen can be used to combat canine mycotic dermatitis.
  • ThesisItemOpen Access
    Comparative evaluation of economic losses due to poultry coccidiosis using conventional anticoccidials and alternates in Uttarakhand state
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-07) Sangeeta; Bhatt, Prakash
    The present work was conducted to study the prevalence of coccidiosis in commercial broiler and layer farms located in different rearing region in Uttarakhand state (Garhwal and Kumaun region) from August 2018 to March 2019. Anticoccidial efficacy of 50% hydromethanolic extract of Ageratum conyzoides was evaluated in a commercial poultry farm and compared with Amprolium. The economic loss was assessed with help of various parameters viz. chemoprophylaxis cost, chemotherapeutic cost, mortality loss, reduced body weight gain, increased FCR etc. in broilers. Total economic losses were `7,171 in herbal treated group as compared to amprolium treated group it was `7,317. A total of 34 commercial poultry farms were screened and 8 were found positive for coccidiosis. The overall prevalence of coccidiosis was 23.52% in Garhwal and Kumaun region of Uttarakhand district. The identification of the coccidian parasite was confirmed by gross lesion site, oocyst morphology and sporulation time of oocyst. Clinical signs included bloody droppings, ruffled feather, anemia, intestinal hemorrhages. Anticoccidial activity of 50% hydromethanolic extract of Ageratum conyzoides plant (herbal drug) was assessed and compared the activity with the standard anticoccidial drug Amprolium. It was concluded from the study that 50% hydromethanolic extract of Ageratum conyzoides @ 1000 mg/kg body weight for 7 days revealed better anticoccidial activity against mixed infection of different Eimeria species namely E. tenella, E. acervulina, E. maxima E. mitis in broiler which was comparable with Amprolium.
  • ThesisItemOpen Access
    Diagnosis and clinico-therapeutic studies on canine hepatic dysfunction
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2019-07) Jeena, Anjali; Rajora, V.S.
    The present was undertaken with the objectives of diagnosing hepatic dysfunction on basis of clinical, hematobiochemical, digital imaging and monitoring the therapeutic response to different regimens. For this, a comprehensive study was undertaken on 18 dogs suffering from hepatic dysfunction. Hepatic dysfunction was found to be predominant in the dogs of senile age group >8years (33.33%), followed by 4- 8 years (27.78%), <1 year (22.22%) and 1-4 year (16.67%). Breed wise occurrence revealed that most hepatic dysfunction cases were in Labrador Retriever (22.22%). Sex wise occurrence revealed that males (61.11%) were predominantly affected than females (38.88%). Clinical manifestations recorded in hepatic dysfunction were lethargy to depression, anorexia, vomition, pale mucosa, diarrhoea, polyuria/polydipsia, pain on abdominal palpation, fever, ascites, icterus, peripheral oedema, emaciation, melena, and petechial haemorrhages. The overall haemato-biochemical changes of dogs with hepatic dysfunction revealed anaemia, neutrophilic leukocytosis, prolonged prothrombin time, hypoproteinemia, hyperbilirubinemia and rise of serum liver enzymes (ALT, AST, ALP and GGT). The acute hepatic dysfunction had significantly higher albumin level than globulins level as compared to the chronic hepatic dysfunction. Hepatic radiography and ultrasonography were very useful in diagnosing hepatic dysfunction; however, with ultrasonography, detailed information pertaining to the liver dysfunction could be obtained. The presence of bilirubinuria and bilirubin crystals in the urine was suggestive of canine hepatic dysfunction. In the therapeutic management of hepatic dysfunction, incorporation of Ursodeoxycholic acid and SAMe with silybin (Lisybin) to therapy enhances clinical improvement in hepatic dysfunction and helps restoring normal haemato-biochemical values. Regular screening of apparently healthy dogs will help in early detection of hepatic dysfunction.
  • ThesisItemOpen Access
    Epidemiology, clinico-pathological and therapeutic studies on canine babesiosis in tarai region of Uttarakhand
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2018-05) Kunwar, Vidhi; Bhatt, Prakash
    The present study was under taken in two heads viz. clinico-epidemiological study and therapeutic study for the epidemiological study data was collected from different veterinary hospitals in and around Tarai region of Uttarakhand. The overall prevalence of canine babesiosis was recorded as (23.63%) out of which 55.44% dogs were infested with ticks on hospital records. Canine babesiosis was more prevalent in Pantnagar area (28.82%) and least prevalent in Lalkuan region (18.87%). It was most prevalent in males (25.89%) as compared to female dogs (19.74%). The maximum prevalence was seen in German shepherd (29.03%) and minimum prevalence in bull mastiff (5.25%). Young dogs of 1 to 3 years of age were comparatively more affected as compared to adult dogs. The highest prevalence was found in the month of July (33.33%) whereas least was recorded in the month of December (8.04%). High rise of temperature, tick infestation, anorexia, dehydration, lethargy, etc. were the characteristic clinical signs recorded from dogs suffering with babesiosis. For therapeutic study 18 dogs positive for babesiosis were randomly divided into three equal (group I to III) and referred as infected groups. One group with six healthy animals was taken as control (group IV). Dogs of group I, II and III were administered Dimenazine aceturate, doxycycline + clindamycin and Imidocarb dipropionate respectively at prescribed doses along with symptomatic and supportive medication. Various hemato-biochemical parameters viz. Hb, TEC, PCV, platelet, neutrophils, eosinophils, lymphocyte count, total protein, albumin, globulin, glucose, ALT, AST, ALP, BUN, Creatinine and total bilirubin were recorded at 0, 7, 28 day of study in infected groups. There was significant decrease in Hb, TEC ,PCV, platelet, neutrophils, total protein, albumin, globulin and glucose while significant increase in eosinophils, lymphocyte count, ALT, AST, ALP, BUN, Creatinine and total bilirubin in infected groups at different intervals. The study revealed that all the drugs under study could clear the babesia spp. infections from the affected dogs, however, based on the clinical improvement and lowered degree of parasitemia in diminazene aceturate was considered as the most efficacious drug against babesiosis followed by Imidocarb dipropionate and Doxycycline and clindamycin combination therapy.
  • ThesisItemOpen Access
    Prevalence of neonatal diseases of caprine with special reference to neonatal septicemia in Nainital and U.S Nagar districts of Kumaon region
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2018-06) Bhujel, Suchitra; Singh, J.L.
    The present study was undertaken to study the prevalence of neonatal diseases of caprine and clinico-pathological and therapeutic studies of Neonatal Septicemia in Nainital and U.S Nagar districts of Kumaon region. The prevalence study revealed an overall prevalence of Neonatal diseases to be 47.52 % and overall mortality of 12.16 %. Maximum morbidity was due to Enteritis (43.89 %) followed by Pneumonia (22.04 %), Pneumo-enteritis (21.25%), Neonatal Septicemia (9.44 %), Miscellaneous condition (2.36 %) and Congenital defects (0.98%). With respect to season and sex, highest morbidity was seen in winter season (51.77 %) and in males (52.16 %). Mortality rate was also highest in winter season (56.15 %) and in male kids (54.61 %). Out of 120 blood samples cultured, 48 samples were positive for Septicemia, of which 41 were due to gram negative bacteria and 7 were due to gram positive bacteria. Kids infected with Neonatal Septicemia showed signs of depression, inappetance, absence of suckling reflex, dehydration. Diarrhoea, omphalitis and arthritis was also seen in most of the kids. A significant (P≤0.05) increase in temperature (104.89±0.33˚F), heart rate (128.37±3.96 beats/min) and respiration rate (37.72±1.7/min) was seen in all kids before treatment. Hemogram revealed leukopenia (6.38±0.45 x103/μl) and neutopenia (1.68±0.16 x103/μl) with no significant changes in Hb (11.22±0.40gm/dl), PCV (31.87±1.45%) and TEC (12.72±0.76 x 106μl). Biochemical analysis revealed a significant (P≤0.05) decrease in serum protein (5.37±0.19 gm/dl), albumin (2.63±0.11gm/dl), IgG (15.29±2.04 mg/dl) and glucose (42.68±1.08 mg/dl) with significant (P≤0.05) increase in serum creatinine (1.73±0.6 mg/dl), BUN (27.66±1.1 mg/dl), ALT (21.62±1.46 U/L), AST (516.20±27.88 U/L), ALP (124.15±6.44 U/L) and LDH (441.45±17.37 U/L). Based on recovery and therapeutic scoring Ceftriaxone + Tazobactum (6.469) were graded superior to other anti-microbials. Amoxicillin + Sulbactum (6.424) showed better recovery but based on total score it was graded 2nd followed by Marbofloxacin (6.391) and Amikacin (6.345) respectively.
  • ThesisItemOpen Access
    Elemental analysis of urinary calculi in dogs (Canis familiaris)
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2018-08) Pooja; Das, Arup Kumar
    Urinary calculi have been recognized as one of the most painful disease in companion animals and treatment for urolithiasis in dogs and cats has been the province of the veterinary surgeon. The cases of canine urolithiasis have been treated with various modes. The knowledge of urinary stone composition is important for understanding pathophysiology, choice of treatment modality, and prevention of recurrence of urolithiasis. For elemental analysis of urinary calculi twenty clinical cases of obstructive urolithiasis in dogs were used. Clinical, ultrasonographic and radiographic examinations were conducted for diagnosis of disease. The choice for operative technique was governed by the level of obstruction in the lower urinary tract and physiological state of the patient. The spatial distribution of major and trace elements in the surgically retrieved uroliths were studied using scanning electron microscopy with elemental distribution analysis (SEM-EDAX). SEM-EDAX was found to be very important tool in assessing stone composition. Seventeen elements were recognized and quantified (viz. O, P, C, Ca, Mg, N, K, Cs, Na, Al, S, Cl, Ni, Zn, Si, Fe and Ti). On statistical analysis of elemental composition urinary stones dog-patients were broadly classified into two groups, where urine stones of thirteen dog patients wise clustered in one group while the stones of rest seven patients were clustered in other groups. The combination identified not only the molecular species present in the calculus, but also the crystalline forms within chemical constituents. Using EDAX, the amount of calcium, phosphorus, oxygen and carbon present in the stone sample could be well understood. Based on similarity in composition of the urinary calculi the dog patients were further divided into different subgroups. These results indicated that formation of similar type of calculi in different dog patients might be due to their food habit, breeds, ages, sexes, urine pH. These types of information are very useful in diagnosis for the treatment of such diseases. Inferences can be drawn that – (i) evaluation of the surface characteristics of uroliths may be helpful in the prediction of their mineral composition. (ii) SEM with an appropriate magnification, one can study the morphology and the crystal structure of various urinary stones and elemental distribution analysis (EDX) makes it possible to confirm the results of SEM and also percentage of different elements present in stone sample can be evaluated.
  • ThesisItemOpen Access
    Studies on anorexia syndrome in large ruminants with reference to etiology, prevalance and therapeautic management
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2018-05) Bisht, Nitish; Shukla, S.K.
    The present study was aimed for studying prevalence, clinico-hematobiochemical and therapeutic management of anorexia syndrome in large ruminants in and around Pantnagar of Uttarakhand state. Overall incidence of anorexia related to digestive disorders and due to haemoprotozoan disease in large ruminants was 29.54% and 27.72% respectively. Before the treatment, pH of rumen liquor was slightly acidic and rumen motility reduced substantially in all the treatment groups. Pre-treatment rumen liquor examination revealed reduced microbial count and activity, reduced total protozoal count, protozoal motility, bacterial count and amount of TVFA in rumen liquor and increase in time values for MBRT, SAT and Nitrate reduction test in both diseases. Hemogram with leukocytosis, neutrophilia and lymphocytopenia suggestive in animals suffering from digestive disorders while anorexia related to haemoprotozoan disease revealed leukocytopenia and slight lymphocytosis with change in haemoglobin. Alterations in biochemical parameters included significant (P_0.05) increase in serum ALT, AST, LDH and BUN concentrations and reduced serum glucose levels in both type of disorders in diseased animal. Recovery in anorexia due to digestive disorders was 100% in all groups while recovery due to haemoprotozoan group it was around 50% in group III, 66.66% in group II, IV, VI and 83.33% in group V. Based on the clinico-therapeutic study lyophilized rumen liquor was graded as a superior treatment followed by air dried rumen liquor in both diseases, while Ecotas, Rumen FS and Fastune respectively for rumen disorder whereas Fastune, Ecotas and Rumen FS haemoprotozoan disease respectively.
  • ThesisItemOpen Access
    Epidemiological and clinico-therapeutic studies on exocrine pancreatic insufficiency in dogs
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2017-07) Singh, Anand Kumar; Bhatt, Prakash
    The present investigation was undertaken to assess the prevalence of exocrine pancreatic insufficiency (EPI) in dogs and their clinicotherapeutic evaluation. Out of total 1503 dogs registered during the study period from Pantnagar and adjoining area, 961dogs were presented with gastro intestinal disorders. For the epidemiological study, 386 dogs irrespective of age, sex and breed, history of anorexia, vomition, weakness, abdominal pain, diarrhea and dehydration were examined. The dogs were preliminary declared positive for EPI on the basis of faecal trypsin test and presence of starch and neutral fat in faeces. The positive animals were further grouped for clinicotherapeutic study. A total of four groups were made with five dogs in each group. The group I dogs, received no treatment and served as healthy control. The group II dogs received pancreatin 200 mg and simethicone 40mg combination for 45 days. The group III animals received 15,000 units of USP amylase activity, 4,000 USP of lipase activity and 15,000 USP units of protease activity for 45 days. The group IV dogs received 1,00,000 armour units of enzyme activity supplied by a purified concentration which has a specific trypsin and chymotrypsin activity in the ratio of approximately six to one for 45 days. The EPI affected dogs were also administered symptomatic and supportive treatment. Haematological parameters viz. Hb, PCV, TEC, TLC, DLC, serum lipase and canine pancreatic lipase (cPL) were estimated at regular interval i.e. on 0th, 15th, 30th and 45th day of the study. The overall prevalence of EPI was found to be 0.99% on faecal analysis basis. However on serum lipase and canine pancreatic lipase activity it was found to be 0.46 and 0.40%, respectively. The clinical prevalence on faecal analysis was recorded to be 3.88% and on serum lipase and cPL basis was 1.82 and 1.56%, respectively. The maximum prevalence was observed in dogs aged 5 years and above and maximum prevalence was recorded in German shepherd dogs. All the infected group dogs exhibited significantly high level of Hb and PCV due to haemoconcentration. The leukocytic indices also showed a significant increase in leukocyte and neutrophils count as compared to healthy control. No significant change in cells of erythrocyte and leukocyte indices was recorded within groups at different intervals except neutrophil, leukocyte and lymphocyte count in treated groups. The serum lipase and cPL levels were also significantly increased in all infected groups as compared to healthy control. However, no significant difference in the number of serum lipase and cPL positive cases were observed. It can be concluded from present study that EPI has moderate clinical prevalence in and around Pantnagar region of Uttarakhand. Dogs receiving 1,00,000 armour units of enzyme activity supplied by a purified concentration which has a specific trypsin and chymotrypsin activity showed better results followed by 15,000 units of USP amylase activity, 4,000 USP of lipase activity and 15,000 USP units of protease activity.