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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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1991 - 19968
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Subject: Veterinary Surgery and Radiology × End date: 1996 × Start date: 1990 × Type: Thesis × Thesis Type: M.V.Sc. ×
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Now showing 1 - 8 of 8
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    ThesisItemOpen Access
    THERAPEUTIC EFFECT OF EPIPLEURAL AND VISCERAL PROCAINE BLOCKADE IN PRIMARY INDIGESTION CASES OF BUFFALOES (Bubalus bubalis)
    (AAU, Anand, 1991) Shah, Dharmendra A.; Parsania, R. R.
    The cases admitted to Veterinary College Hospital, Anand and Ambulatory Clinic centres at Chikhodra, Gamdi and Bedva villages were studied and 50 oases of primary indigestion were selected for therapeutic trials. The cases were grossly diagnoses on the basis of history, clinical findings and faecal sample examination. These 50 animals were divided equally into five treatment trial groups via., (a) epipleural procaine blockade (b) viscera procaine blockade (c) conventional method supplemented with epipleural procaine blockade (d) conventional method supplement with visceral procaine blockade and (e) conventional method onl Clinical observations regarding overall behaviour of the animal, its expression, ruminal motility, heart rate, respiratiorate and rectal temperature were studied before and 48 hours aft the treatment in all the five groups of buffaloes. Haematologica parameters (Hb, PCV, TEC, TLC and DLC), biochemical parameters (blood glucose and BUN) and rumen fluid analysis (colour, odour, pH, protozoal motility and total volatile fatty acids concentrate were also studied before and 48 hours after the treatment. However, in all the parameters, the changes were found non-significant and remained within their normal physiological limits. Depending upon the efficacy and the rapidity with which the cases got cured, the present study has definately indicated that the procaine blockade was better than the conventional treatment. Among procaine blockades also, the visceral procaine blockade was found to be superior and practical method having wide field applicability. The present study was restricted to fifty clinical cases of primary indigestion only. But looking to the results achieved this visceral procaine blockade can be employed in more number of cases and also in variety of conditions, which may throw a light on some hidden efficacy of the same. So, further study is needed for better understanding of the blockade and i t s wide sprea uses in veterinary practices.
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    ThesisItemOpen Access
    STUDIES ON PROTECTIVE EFFECT OF DIMETHYL SULFOXIDE (DMSO) IN EXPERIMENTALLY INDUCED INTESTINAL ISCHEMIA IN CALVES
    (AAU, Anand, 1993) Garara, Shailesh V.; Jani, B. M.
    The experiment was conducted on twelve 6 to 12 months old cow calves to judge the nature and extent of reperfusion injury after intestinal ischemia and to evaluate protective effect of dimethyl sulfoxide (DMSO), All the animals were subjected to one complete and one incomplete ischemic strangulation obstruction (ISO) of about 25 cm jejunal segments for the duration of 6 hours. After 6 hours of ischemia, reperfusion of the intestinal segments was established by releasing the vascular obstructions. The animals were randomly divided into two equal groups (Group A and B), The animals of Group A served as control ones and no treatment was carried out at the time of reperfusion, while animals of Group B were given 20 per cent DMSO solution in normal saline intravenously at the rate of 2 g/kg body weight at the time of reperfusion. The protective effect of DMSO was ascertained by evaluating standard clinical criteria, fluorescent pattern and histopathological findings at 24 hours reperfusion period. Physical changes like malaise, dullness, depression, change in rectal temperature, respiration rate and heart rate were of no significance either in ascertaining ischemic damage or in evaluating the protective effect of DMSO. Grossly, serosa of ischemic segments in control group revealed severe degenerative changes including moderate to severe adhesions, oedema and congestion, and reddish colouration while that of treated segments showed absence of adhesion, pinkish colour, hyperemia and slight oedema and congestion. Similarly mucosal changes were severe in control segments and were of very mild degree in treated segments. Following fluorescein dye injection, the treated segments showed viable fluorescent pattern while that of control segments showed non-viable fluorescent pattern. Histopathologically, control segments showed stunted mucosal villi lined by low columnar to cuboidal epithelial cells with few villi naked. The lumen contained desquamated epithelial cells with haemorrhages. Mucosa of treated segments was almost normal. Degenerative changes in submucosa, lamina propria and serosa were severe in control group while these clianges were either absent or were of very mild degree in treated segments. Based on SCC, fluorescein dye technique, and histopathological observations, it was-concluded that the intravenous DMSO therapy at the time of reperfusion could be a safe and effective supplementary therapy to combat ischemic intestinal disorders in cattle.
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    ThesisItemOpen Access
    STUDIES ON INDUCED PERITONEAL ADHESIONS IN BOVINES WITH SPECIAL REFERENCE TO USE OF SODIUM CARBOXYMETHYLCELLULOSE FOR THEIR PREVENTION
    (AAU, Anand, 1994) Thakker, Haresh M.; Parsania, R. R.
    An experimental study was conducted on 12 healthy male buffalo calves to study the effects of sodium carboxymethylcellulose in minimising induced intraperitoneal adhesions. In all the animals, adhesions were induced by crushing the jejunal serosa with Allis tissue forceps and placing a chromic catgut suture in middle of the traumatized area. In the treatment group (II) consisting of six animals, one per cent solution of sodium carboxymethylcellulose was infused intraperitoneally @ 7 ml/kg body wt. immediately following surgery. In other six calves (Group I, control) no treatment was given. Postoperatively all calves were observed for 14 days.
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    ThesisItemOpen Access
    THERAPEUTIC EVALUATION OF DIMETHYL SULFOXIDE (DMSO) IN ENDOTOXIN INDUCED ARTHRITIC BUFFALO CALVES
    (AAU, Anand, 1992) Goti, Bharat S.; Jani, B. M.
    The experiment was undertaken in buffalo calves to study the clinicopathologic changes of E. coli LPS (endotoxin) induced arthritis and to evaluate therapeutic efficacy of intra-articular medical grade dimethyl sulfoxide (DMSO). The experiment was conducted on twelve buffalo calves into two equal groups (A and B). In all the animals, arthritis of right radio-carpal joint was induced successfully by intra-articular administration of E.coli LPS at the dose rate of 0.4 ug/kg body weight. Group A served as control and no treatment was given. In group B, 2 ml of 50 per cent DMSO in saline was injected intra-articular at 2, 10 and 24 hours after induction of arthritis.
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    ThesisItemOpen Access
    STUDIES ON XYLAZINE AS AN EPIDURAL ANAESTHETIC AGENT IN BUFFALO CALVES (Bubalus bubalis)
    (AAU, Anand, 1991) Patel, Bharat K.; Parsania, R. R.
    A study on epidural analgesia using xylazlne was conducted In 18 healthy buffalo calves, divided Into three groups of six animals each, Xylazlne was administered @ 0.06 mg/kg (group I), 0.08 mg/kg (group II) and 0.1 mg/kg body weight (group III). The Induction time, onset of salivation, sitting time, standing time, duration and quality of anaesthesia and complete recovery time were recorded In each animal. In all the groups, there was a significant reduction In heart rate and respiration rate. However, It reached near to the preadministration level by 4 hours after administration. There was no significant effect on rectal temperature and it remained more or less within the normal range. Haematological study revealed significant reduction In all the parameters viz., TEC, TLC, PCV and Hb concentration,The changes were more marked upto 4 hours after administration which reduced in their Intensity from 8 hours post administration. Biochemical studies revealed significant Increase in blood glucose in all the groups after 1 hour of injection and it returned to near normal level after 24 to 48 hours. The BUN showed non-significant and fluctuating decreasing trends throughout the period of study. The values of serum creatinine were found within normal physiological range. The enzymes SGOT, SGPT, AKP and ACP did not show any significant alterations. The present study indicated that the xylazlne is an effective analgesic agent which can be safely used by epidural administration.
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    ThesisItemOpen Access
    STUDIES ON EPIPLEURAL AND PARANEPHRIC NOVOCAINE BLOCKADE IN PRIMARY INDIGESTION OF BUFFALOES
    (AAU, Anand, 1991) Prajapati, Ashish K.; Jani, B. M.
    Primary indigestion in buffaloes is one of the most commonly encountered clinical problems causing considerable loss of milk production. Conventional therapy for this malady often gives unconsistent result and prolonged treatment is invariably required. In order to evolve a better therapeutic regime and to cut short course of treatment, therapeutic trials were conducted in fifty clinical cases of primary indigestion in buffaloes attended at Veterinary College Hospital, Anand and ambulatory clinic centres at Chikhodra, Gamdi and Bedva villages using non-specific pathogenetic method of therapy in the form of procaine (novocaine) blockade. These animals were divided randomly into five treatment groups , each group consisting of ten animals, Eipipleural novocaine blockade, paranephric novocaine blockade, conventional treatment supplemented with epipleural blockade, conventional treatment supplemented with paranephric blockade and conventional treatment alone using irumenotoric drugs and vitamin B-complex with liver extract were given in group) I, II , III , IV and V respectively. Animals of groups III and IV comprised those cases which had failed to respond favourably to the conventional therapy and subsequently they were supplemented with epipleural and paranephric blockades respectively. Clinical parameters like time taken for return of normal appetite, increase in ruminal motility and milk production as well as changes in heart rate, respiration rate and rectal temperature were studied before and 48 hours after the treatment in all the groups. Overall response to the treatment was categorized as very good, good, fair and poor. Ruminal fluid analysis including change in colour, odour, pH, protozoal motility and total volatile fatty acid concentration were studied in all the animals before and 48 hours after treatment. Haemogram included the study of haemoglobin concentration, packed cell volume, total leucocyte count, total erythrocyte count and differential leucocyte count. Biochemical parameters viz., blood glucose, blood urea nitrogen, total proteins and total cholesterol were also studied before and 48 hours after treatment in all the animals. Excellent clinical response was observed in the animals given epipleural and paranephric novocaine blockade with maximum number of animals falling into the very good category. Even animals of groups III and IV which were refractory to the conventional therapy also showed very good clinical improvement. Restoration of appetite and milk production to presickness level was evident within 24 to 48 hours in these animals with treatment given only once« Again out of these two blockades, paranephric novocaine blockade was found to be superior and easier to perform than epipleural novocaine blockade. Response to conventional therapy alone was not uniform and varied greatly with maximum number of animals falling into fair and poor categories. It also required prolonged and daily administration of drugs. Longer time was taken in restoration of milk production and in a few animals it did not even reach to presickness level. No significant changes were observed in other clinical, ruminal fluid, haematological and biochemical parameters in any of the treatment groups. However, minor fluctuations within the physiological limits were observed in some of these parameters. The study clearly showed effectiveness of novocaine blockade therapy over the conventional therapy in treating primary indigestion of buffaloes.
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    ThesisItemOpen Access
    EVALUATION OF Typha angustata AND Prosopis juliflora AS WOUND HEALING AGENTS IN CATTLE-CLINICAL, BIOMECHANICAL AND HISTOLOGICAL STUDIES
    (AAU, Anand, 1994) Patel, R. S.; Parsania, R. R.
    Each of 12 healthy crossbred male cow calves were subjected to ten excisional wounds, five on each side of thoracolumbar region to evaluate the wound healing property of Typha angustata, Prosopis juliflora and an ayurvedic ointment Swellnil , The wound healing was evaluated clinically, and by histological and biomechanical examination of excised healing tissue, collected at 7, 14 and 28 days. Granulation of tissues was evident on 4 to 6th day; contraction and epithelialization on 7 to 9th day and complete healing between 21 and 23 days. Extensive fibroblastic proliferation, high vascularity, non-significant acid phosphatase and alicaline phosphatase activities, intense mucopolysaccharide concentration and thin collagen fibres were observed in histological examirmtion at early stage of healing. At later stage, marked reduction in cellularity, vascularity and mucopolysaccharide concentration, increased acid phosphatase and alkaline phosphatase activities, matured collagen fibre bundles and elastic fibres were observed. Biomechanical study revealed increase in tensile strength with progress in healing, whereas extensibility increased on 14th day, but decreased on 28th day. No significant difference was observed between treatments as well as control in clinical, histological and biomechanical studies. In clinical trials conducted in 51 cases complete healing was observed between 8 and 22 days. The laboratory examination of the swabs collected periodically from the wounds showed presence of microorganisms upto 6 days in P. juliflora treated wounds and upto 9 days in T. angustata and Swellnil treated wounds. The microorganisms identified from the clinical wounds were Staphylococcus aureus (14), Staphylococcus (non-coagulase) (1), Streptococcus spp. (9), Escherichia coli (6), Proteus spp. (10), Corynebacterium pyogens (3)Klebsiella spp. (2), Pseudomonas spp. (3) and yeast (5). No distinct difference was observed in the healing period of wounds treated with three different ointments. Prom the present study it can be concluded that the T.angustata, P.juliflora and Swellnil ointments have no deleterious effect on wound healing. In clinical cases they help in normalization of the healing process.
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    ThesisItemOpen Access
    COMPARISON OF EFFICACY OF GENTAMICIN TREATMENT IN CONJUNCTION WITH DIMETHYL SULFOXIDE LAVAGE AND NORMAL SALINE LAVAGE TREATMENT FOR E. COLI INDUCED ARTHRITIS IN COW CALVES
    (AAU, Anand, 1996) PARANDEKAR, ABHIJIT D.; Parsania, R. R.
    The experiment was undertaken in eighteen cow calves allotted to three equal groups (A, B and C) to study the clinicopathologic changes of E. coli induced infectious arthritis and to evaluate gentamicin treatment in conjunction with 10 per cent dimethyl sulfoxide (DHSO) lavage and normal saline lavage. In all the animals, arthritis of tibiotorsal joint was successfully induced by intra-articular administration of 5 ml of inoculum containing 4 x 10 organisms per ml. Group A served as control and no treatment was given. Animals of Group B were treated with through and through joint lavage with 500 ml 10 per cent DMSO in conjunction with 100 mg gentemicin intra-articularly and animals of Group C were treated with through and through joint lavage with 500 ml normal saline and 100 mg gentamicin intra-articularly at days 2, 4, and 6 after induction of arthritis. Intramuscular gentamicin @ 5 mg per kg body weight was given from day 2 to 6 after induction of arthritis in Groups B and C. Clinical symptoms like rectal temperature, heart and respiratory rates and joint circumference were recorded before (day 0) and on days 1, 2, 3, 4, 6, 8 and 15 after induction of arthritis. Various synovial fluid parameters viz., TLC, TP and MPQ were analysed before (day 0) and on day 2, 4, 6, and 15 after induction of arthritis. Bacteriological examination of synovial fluid was carried out on day 2 after induction of arthritis. Gross and histopathological examination of joint capsule and articular cartilage was also carried out after euthanizing the animals on day 15 after induction of arthritis. Vital signs were increased on day 1 after induction of arthritis in all the three groups. Thereafter from day 2 onwards it started declining and there was no significant difference amongst the three groups. Joint circumference progressively and significantly increased from day 1 after induction of arthritis to day 4 in animals of Group A and thereafter started declining but remained significantly higher as compared with base value. Similar changes in joint circumference were observed in Groups B and C but the peak value was seen on day 3 after induction of arthritis and at the termination of the study the joint circumference of Group B did not differ significantly from base value. While in the animals of Group C joint circumference was significantly more than that of base value and slightly low as compared to that of Group A. Synovial fluid revealed marked changes in its cytological and biochemical properties after induction of arthritis. There was significant increase in TLC and TP, and significant reduction in MPQ score. The TLC and TP showed gradual decrease from day 4 onward as compared to day 2 after induction but remained higher than that of base value. The MPQ score gradually increased from day 4 after induction of arthritis as compared to that of day 2 in Group A. In Groups B and C also there were marked alterations in above mentioned parameters. But at the termination of the study the TLC and TP were lower in animals of Group B as compared to that of Groups A and C. While in the animals of Group C the values were slightly more than that of Group B and slightly lower than that of Group A. The MPQ score was significantly higher in animals of Group B as compared to Groups A and C. While in animals of Group C MPQ score was slightly low as compared to that of Group B but significantly higher than that of Group A. E. coli organisms were not isolated from synovial fluid samples collected at day 2 after induction of arthritis in all the three groups. The gross examination of open tarsal joint in animals of Group A revealed oedematous synovial membrane, deposition of yellow to brownish coloured fibrin clots in large amount and, in one case, induration of lateral aspect of joint capsule. While in animals of Groups B and C there were no gross lesions except very few amount of fibrin clot accumulated in acute corners of plantolateral and dorsomedial pouches. Gross examination of articular cartilage in animals of Group A revealed loss of glistening appearance of articular cartilage surface of tibiotarsal joint, pitting and erosion of articular cartilage with greater frequency on the articular surface of medial and lateral ridges of trochlea of tibial tarsal bone. The gross lesions of articular cartilage were absent in animals of Groupt B and C. Histopathological examination of joint capsule in animals of Group A revealed moderate intimal hyperplasia, mild to moderate degree of subintimal cellularity, mononuclear infiltration and at places neutrophilic infiltration, subintimal oedema and subcellular fibrin below the intimal layer. These changes were reduced in animals of Group C and markedly reduced in animals of Group B. Microscopic changes of articular cartilage in animals of Group A were characterised by erosion upto calcified zone in one case and showed granulation tissue on the surface and in the intermediate zone of articular cartilage. The microscopic changes of articular cartilage were absent in animals of Groups B and C. Evaluation of various clinical synovial fluid and histopathological parameters clearly indicated the beneficial effect of through and through Joint lavage with 10 per cent DMSO in conjunction with intra-articular gentamicin treatment over through and through joint lavage with normal saline in conjunction with intra-articular gentamicin treatment E. coli induced infectious arthritis of cow calves.