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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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20162
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Subject: Veterinary Surgery × End date: 2017 × Start date: 2016 × Type: Thesis ×
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    ThesisItemOpen Access
    STUDIES ON MANAGEMENT OF CANINE MAMMARY TUMOURS WITH DENDRITIC CELL THERAPY
    (AAU, Anand, 2016) VALA ARSHI KALUBHAI; Dr. P. V. PARIKH
    The present study was carried out with multiple objectives to standardize the treatment protocol for dendritic cell therapy for mammary gland tumours, to study the safety and tolerability of dendritic cell based therapy for the treatment of mammary gland tumour in dogs, and to evaluation of efficacy of dendritic cell therapy in dogs. Twenty three cases of canine mammary tumours were studied in detail. The highest occurrence of canine mammary tumour cases was found in the dogs aged 8 to 12 years (47.82 %) followed by those aged 4 to 8 years (39.13 %). It was least (8.69 %) in older dogs above 12 years and intermediate (4.30 %) in younger dogs less than 4 years of age. Breed wise higher occurrence was found in German Shepherd and Labrador Retriever as compared to other breeds. Cases of mammary tumours were observed only in females (100 %). There was an increasing frequency of canine mammary tumour from cranial thoracic to inguinal pairs with the highest incidence in caudal abdominal (41.17 %) and the least in caudal thoracic pair (2.94 %). Out of the 23 bitches, 95.65 per cent were intact and others were neutered. Radiography of thorax was performed to diagnose tumour metastasis in lung. It revealed absent of metastases in all the cases. Ultrasonography revealed size, irregularities of margins as well as echogenicity of mammary tumour masses with vasculature, helping to differentiate their nature and clinical significance. Haematobiochemical parameters did not show any remarkable variation in the cases of mammary tumours. Dendritic cells immunotherapy (Group 1) was performed in 8 cases. After one month of completion of therapy, size of tumour mass was increased gradually in four cases, in three cases growth remained constant in size and in one case it disappeared. Results of MTT assay and IFNG+ indicated that DC therapy potentiate CMI response in this group of animals. Surgical removal of mammary tumour (Group 2) was performed in 7 cases with good success and recurrence was noticed 2 months later in one case. Surgery followed by DC immunotherapy (Group 3) was performed in 8 cases. After completion of therapeutic protocol every case recovered uneventfully and no recurrence was observed. Data of MTT assay and IFNG+ indicated that DC therapy potentiate CMI response in this group of animals. Based on result, Surgery followed by DC therapy group was proved good compared to immunotherapy group and surgical group. Histopathology of selected 12 cases and FNAB of selected 6 cases of canine mammary tumours studied, 10 (55.55 %) cases were confirmed as benign mammary tumours like Cystic papillary adenoma, Benign mixed mammary tumour, Papillary fibroadenoma, Chondro fibro adenoma and Intra ductal papilloma, while 8 (44.44 %) were malignant mammary tumours like Papillary adenocarcinoma, Malignant myoepithelioma, Solid carcinoma and Malignant mix tumour. From the above study it can be concluded that DC therapy was observed to be safe and well tolerated in all animals without any adverse effects or toxicity. Study provided novel insights on the benefit of DC based cellular immunotherapy for managing mammary tumours in canines. Further studies to improve the therapeutic efficacy of DC therapy in canines are required in the future.
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    ThesisItemOpen Access
    “ULTRASONOGRAPHY OF UDDER AND TEAT IN DAIRY ANIMALS
    (Anand Agricultural University, Anand, 2016) NIRAVKUMAR RAMANBHAI AMIN; Dr. D. B. PATIL
    The present clinical study was undertaken to record the normal and abnormal ultrasonographic appearance of udder and teats in dairy animals in and around Anand. A total of 38 bovines (cow-26; and buffalo-12) were examined clinically including normal (n=24) and affected (n=24) udder and teats.