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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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Subject: Veterinary Pharmacology × End date: 1998 × Type: Thesis ×
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Now showing 1 - 9 of 9
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    ThesisItemOpen Access
    STUDIES ON SOME MEDICINAl PLANTS REPUTED TO HAVE ANTIMICROBIAL ACTIVITY
    (AAU, Anand, 1983) THAKER, ASWIN M.; Anjaria, J. V.
    Ancient Indian literature mentions many indigenous medicinal plants, claimed to posses antimicrobial activity and wound healing property. Specific and detailed investigations to prove their efficacy however, appear to be meagre. Leaves of Azadirachta indica, Annona squamosa, Ocimum sanctum and leaves and stems of Bergia odorata were dried in shade, pulverised to homogenous powder, and proximate chemical analysis was done. Solidified chloroform extracts of all plants dissolved in propylene glycol were used for in vitro inhibition of microbial growth on Staphylococcus aureus, Streptococcus pyogenes, Corynebacterium spp. Escherichia coli and Pseudomonas aeruginosa by 10 fold serial dilution of incubated 5 ml. Glucose broth containing 0.1 ml extract and 0.1 ml inoculum of each organism, and subsequent plating by standard plate count method (SPC).
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    ThesisItemOpen Access
    SOME PHARMACOLOGICAL STUDIES ON THE ISOLATED PRINCIPLES OF LEPTADENIA RETICULATA.
    (AAU, Anand, 1973) ANJARIA, J. V.; GULATI, O. D.
    Abstract not Available
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    ThesisItemOpen Access
    SOME INDIGENOUS DRUGS REPUTED TO HAVE GALACTAGOGUE PROPERTY WITH PARTICULAR REFERENCE TO LEPTADENIA RETICULATA (JIVANTI)
    (AAU, Anand, 1965) Anjaria, J. V.; Gupta, Indra
    Abstract not Available
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    ThesisItemOpen Access
    STUDIES ON ANTIBACTERIAL AND WOUND HEALING PROPERTIES OF PROSOPIS JULIFLORA
    (AAU, Anand, 1991) SARVAIYA, J. G.; Verma, M. P.
    Alcoholic and chloroform extracts of shade dried leaves of Prosopis juliflora, Azadi rachta indica and Adhatoda vasica, as well as juices from fresh green leaves of P.Juliflora were screened for antibacterial activity by disc diffusion method against Staphylococcus aureus, Streptococcus sp. Corynebacterium sp., Escherichia coli , Pseudomonas aeruginosa, Proteus sp. and Klebsiella sp. The extracts from Azadirachta indica and Adhatoda vasica were almost devoid of antibacterial activity. Extracts from P. juliflora leaves possessed antibacterial activity against Staphylococcus aureus, Streptococcus sp., Corynebacterium sp. and proteus sp. However, alcoholic extract was additionally affective against Escherichia coli and Klebsiella sp. The alcoholic extract was more potent than chloroform extract against the susceptible bacteria. However, Pseudomonas aeruginosa were resistant to these extracts. Crude juice prepared from P. juliflora leaves was effective against Staphylococcus aureus, Bacillus sp.. Diplococcus pneumoniae, Corynebacterium sp., Escherichia coli, Pasteurella multocida and yeast whereas Klebsiella sp. and Proteus sp. were resistant.
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    ThesisItemOpen Access
    STUDIES ON THE PHARMACOKINETICS AND BIOTRANSFORMATION OF FENBENDAZOLE AND TRICLABENDAZOLE IN CALVES
    (AAU, Anand, 1994) Roy, Dulal Chandra; Malik, J. K.
    In the present study, detailed pharmacokinetics and biotransformation of FBZ were investigated in healthy buffalo calves and those fed different diets or subclinically infected with nematode parasites. The detailed pharmacokinetics and biotransformation studies of the drugs were carried out in buffalo calves and cow calves after administration of TCBZ and in buffalo calves following co-administration of FBZ with TCBZ. In addition, the influence of diet on the pharmacokinetic behaviour of TCBZ metabolites was investigated in cow calves. Following FBZ administration or ingestion, FBZ, OFZ and FBZSO2 were detected in plasma of buffalo calves. After intraruminal administration of FBZ (7.5 mg.kg-1), the pharmacokinetics of FBZ and its metabolites were best described by a one-compartment open model in subclinically infected and healthy buffalo calves fed different diets.
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    ThesisItemOpen Access
    PHARMACOKINETIC STUDIES OF METRONIDAZOLE IN SHEEP AFTER INTRAVENOUS AND ORAL ADMINISTRATION
    (AAU, Anand, 1992) Patel, H. M.; Thaker, A. M.
    The present Investigation was undertaken to monitor the pharmacokinetics and dosage of metronidazole In sheep following single Intravenous (20 mg/kg body weight) and oral (20 and 50 mg/kg body weight) administration. The therapeutic plasma concentration of metronidazole was maintained upto 4 h following Intravenous administration. Whereas after oral administration at dosage l e v e l s of 20 and 50 mg/kg body weight, it was maintained for 4 and 6 h, respectively. The pharmacokinetics of metronidazole following intravenous administration conformed to a two-compartment open model (except Animal No. I which was described by a one-compartment open model) with a distribution half-life of 0.06 ± 0.01 h, an elimination half-life of 1.40 ± 0.09 h, and a body clearance of 292.32 ± 18.20 ml h.-1 kg-1. The pharmacokinetics of metronidazole following oral administration (20 and 50 mg/kg body weight) was best described by a one-compartment open model. Following oral administration of metronidazole at dosage levels of 20 and 50 mg/kg body weight the absorption and elimination half-lives were 0.08 ± 0.01- 0.08 ± 0.01, 1.51 ± 0.05 - 1.72 ± 0.09 h, respectively. The total body clearance and bioavailability of metronidazole after lower and higher oral dosages were calculated to be 364.81 ± 10.46 - 473.23 ± 19.66 ml.kg-1.h-1 and 72.76 ± 2.84 - 59.08 ± 3.58 per cent, respectively. On comparing two roates of drug administration, the total body clearance was relatively higher following oral administration than that after intravenous administration. The bioavailability of the drug after oral administration was high. So metronidazole can be used effectively by both oral and intravenous routes. A satisfactory intravenous dosage regimens of metronidazole would be 7-13 mg/kg body weight which should be repeated at 12 h intervals, A satisfactory oral dosage regimen of metronidazole would be 9-17 mg/kg body weight which should be repeated at interval of 12 h.
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    ThesisItemOpen Access
    PHARMACOKINETIC STUDIES OF METRONIDAZOLE IN COW CALVES AFTER INTRAVENOUS AND ORAL ADMINISTRATION
    (AAU, Anand, 1991) BHAVSAR, S. K.; Malik, J. K.
    In the present study, pharmacokinetics and dosage of metronidazole were determined in cow calves following single intravenous (20 mg/kg body weight) and oral (20 and 50 mg/kg body weight) administration. As compared to intravenous administration lower levels of metronidazole were estimated in plasma following oral adminis tration . The therapeutic plasma concentration of metronidazole was maintained upto 6 h following intravenous administration. Whereas after oral administration at dosage levels of 20 and 50 mg/kg body weight, it was maintained for 3 and 10 h, respectively, The pharmacokinetics of metronidazole after intravenous administration was best described by a two-compartment open model, following intravenous administration, the distribution and elimination half lives , volume of distribution and total body clearance were 0.07 ± 0.01 h, 1.92 ± 0.05 h, 0.79 ± 0.03 1.kg-1 and 283.49 ± 6.15ml. h-1. kg-1 respectively.
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    ThesisItemOpen Access
    SOME PHARMACOLOGICAL STUDIES ON THE ISOLATED PRINCIPLES OF LEPTADENIA RETICULATA
    (AAU, Anand, 1973) ANJARIA, J. V.; GULATI, O. D.
    Abstract not Available
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    ThesisItemOpen Access
    STUDIES ON THE EFFECT OF INDUCED THEILERIOSIS (Theileria annulata) AND ENDOTOXAEMIA (Escherichia coli) ON THE PHARMACOKINETICS OF OXYTETRACYCLINE IN CALVES
    (AAU, Anand, 1994) Kumar, Rajiv; Malik, J. K.
    In the present study, detailed pharmacokinetics of conventional and long-acting formulations of oxytetracycline were investigated in healthy calves and those infected with T. annulata or given E. coli endotoxin. In addition, clinical, haematological and biochemical effects of T. annulata infection and endotoxaemia and the ability of two different formulations of OTC in reversing the effects induced by the former were thoroughly investigated in cow calves. Theilerioss was induced in calves by subcutaneous administration of ground-up stabilate equivalent to 30 adult ticks (Hyalomma anatolicum anatoUcum) infected with T. annulata. Theileriosis produced an 'acute phase response in calves which was characterized by fever, enlargement of superficial lymph nodes, parasitaemia, anaemia, leucopenia, lymphopenia, hypoglycaemia, hopocholesterolaemia, hypoproteinaemia, bilirubinaemia, azotaemia, hypokalaemia, hyponatraemia, hypocalcaemia, hypophosphataemia, hypozincaemia, hypoferraemia, hypocupraemia, hypomanganesaemia and diminished activity of serum alkaline phosphatase. Conversely, the activities of lactate dehydrogenase, acid phosphatase and aspartate aminotransferase and alanine aminotransferase in serum were significantly elevated. T. annulata infection produced significant alterations in the pharmacokinetic behaviour of OTC administered to calves either by intravenous or intramuscular route. As compared to normal animals, lower levels of OTC were generally estimated in serum of infected calves. In healthy and T. annulata Infected calves the disposition kinetics of OTC was best described by two and one-compartment open models following intravenous and intramuscular administration of conventional and long-acting formulations of oxytetracycline.