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  • ThesisItemOpen Access
    STUDIES ON OCCURRENCE OF HEPATIC AND PANCREATIC DISORDERS IN DOGS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2017-12) HARSHITHA, C.R; Dr. M.L. SATYANARAYANA)
    The present investigation was undertaken to study the occurrence of various pathological conditions in the liver and pancreas of dogs that were presented to the Department of Veterinary Pathology, Veterinary College, Bengaluru. Hepatic lesions were found to be highest in dogs of less than one year, of male sex and non-descript breeds. The lesions were histopathologically classified as vascular changes which include congestion (75.71%), haemorrhage (68.57%) and haematoma (1.42%). Degenerative and necrotic changes which included cell swelling (4.28%), hydropic degeneration (17.14%), fatty change (18.57%) and necrosis (20%). Inflammatory changes included hepatitis (17.14%) and cirrhosis (35.71%). Proliferative changes were hyperplasia of hepatocytes (12.85%) and biliary epithelium (27.14%) and neoplasia (2.85%). Miscellaneous conditions were hemosiderin (28.57%), calcium (2.85%) and bile pigment (20%) deposition. Pancreatic lesions were found to be highest among dogs of above 12 years (22.72%), of male sex (54.54%) and non-descript breeds (36.36%). Microscopically, exocrine pancreatic lesions were classified as vascular changes like congestion (56.81%), haemorrhage (25%) and oedema (4.54%). Degenerative and necrotic changes included degeneration of acinar cells (47.72%), parenchymal necrosis (45.45%), pancreatic fat necrosis (4.54%) and acinar calcification (6.81%). Inflammatory changes recorded were acute (6.81%) and chronic pancreatitis (31.81%). Proliferative changes included hyperplasia of acinar cells (6.81%) and neoplasia (15.90%). Endocrine pancreatic lesions were classified as congestion (11.36%), hypocellularity (18.18%), hypercellularity (11.36%), vacuolar degeneration (25%) and neoplasia (2.27%). Thus, this study concluded that large number of cases revealed abnormality upon microscopic than gross examination, suggesting the need for histopathological evaluation to arrive at accurate diagnosis.
  • ThesisItemOpen Access
    PATHOLOGICAL STUDIES OF OCHRATOXICOSIS AND ITS AMELIORATION USING DIATOMACEOUS EARTH AND VITAMIN E IN BROILER CHICKENS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2016-05) DHEERENDRA NAIK; M. L. SATYANARAYANA; G. V. SUDHAKAR RAO; H. D. NARAYANASWAMY; SUGUNA RAO; S. YATHIRAJ; S. G. RAMACHANDRA
    The study was conducted to evaluate the pathological and immunosuppressive effect of ochratoxin (OA) in broiler chicken and its amelioration using diatomaceous earth (DAE). Experimental ochratoxicosis was induced in broilers with 1 ppm and the ameliorating effects of DAE @ 2000mg/kg feed and Vitamin E 80ml/kg of feed was studied for 35 days. Feeding of ochratoxin caused significant reduction in the body weight gain and feed efficiency. Supplementation of DAE and Vitamin E showed improvement in performance parameters. Ochratoxicosis showed significant increase in relative weights of liver, kidneys and spleen whereas, the weights of bursa of Fabricius and thymus was reduced. Significant improvement in the organ weight was observed in DAE Vitamin E and their combinations supplemented birds. The serum levels of total protein and albumin were significantly lowered whereas, creatinine, AST, ALT and ALP were higher in toxin fed birds. The HI titres against NDV and antibodies against IBD, DAE and Vitamin E supplementation showed improvement in HI titre, against ND and antibodies against IBDV. Microscopic lesions, characteristic to ochratoxicosis were prominent in kidneys, liver and lymphoid organs. Supplementation of DAE and Vitamin E reduced the severity of lesions in these organs. Dietary inclusion of ochratoxin caused hepato-renal and immunotoxicity in birds. However, supplementation with DAE and Vitamin E was helpful in ameliorating the adverse effects of ochratoxicosis in broilers.
  • ThesisItemOpen Access
    PATHOMORPHOLOGICAL AND BIOCHEMICAL EVALUATION OF METHOTREXATE INDUCED HEPATO-TOXICITY AND ITS AMELIORATION BY EUGENIA JAMBOLANA IN RATS
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2016) VIJAYA KUMAR, N
    The liver plays a pivotal role in maintenance and regulation of homeostasis of the body.
  • ThesisItemOpen Access
    STUDIES ON CONTAGIOUS ECTHYMA IN SHEEP AND GOATS
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2017) SYEDA .SUMAIYA
    Sheep farming is one of the important agri-based activities, which has been practiced by a large section of farmers in developing countries like India
  • ThesisItemOpen Access
    STUDIES ON INDUCED DIABETES IN RATS AND EVALUATION OF EFFICACY OF Ocimum sanctum IN ITS CONTROL
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2015) SIMITHA JOHN
    Diabetes mellitus is a chronic metabolic disorder characterised by a high blood glucose concentration-hyperglycemia caused by insulin deficiency
  • ThesisItemOpen Access
    EVALUATION OF HEPATOPROTECTIVE EFFECT OF AGED GARLIC IN AFLATOXIN B1 INDUCED LIVER DAMAGE IN RATS
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2010) SARVESHA, K
    Garlic (Allium sativum) is an important medicinal herb and is known to possess scientifically proven medicinal properties
  • ThesisItemOpen Access
    EXPERIMENTAL PATHOLOGY OF T-2 TOXICOSIS AND MYCOPLASMAL INFECTION IN BROILER CHICKENS
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2010) SANJEEVAKUMAR LALASANGI
    Poultry industry in India, especially broiler production has made phenomenal growth over the past two decades contributing significantly to agri-based economy.
  • ThesisItemOpen Access
    STUDIES ON INDUCED DIABETES IN RATS AND EVALUATION OF EFFICACY OF Azadirachta indica IN ITS CONTROL
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2015) LAKSHMI, H.A
    Diabetes mellitus is regarded as one of the most serious metabolic pandemic of the 21st century
  • ThesisItemOpen Access
    PATHOMORPHOLOGICAL AND BIO-CHEMICAL EVALUATION OF EFFECT OF CHROMIUM IN STREPTOZOTOCIN INDUCED DIABETES IN RATS
    (Karnataka Veterinary Animal And Fisheries Sciences University, Bidar, 2014) R. Y. GURIKAR
    Diabetes is a chronic metabolic disorder characterized by hyperglycaemia and disturbances in carbohydrate, fat and protein metabolism