Thumbnail Image

Theses (PG)

Browse

20201
Reset filters
Subject: Veterinary Pathology × Author: KAVYASHREE, T.L × End date: 2020 × Start date: 2010 × Thesis Type: M.V.Sc. ×
Reset filters

Search Results

Now showing 1 - 1 of 1
  • Thumbnail Image
    ThesisItemOpen Access
    STUDIES ON INDUCED DIABETES IN RATS WITH SPECIAL EMPHASIS ON COMBINED EFFICACY OF Gymnema sylvestre AND Momordica charantia EXTRACTS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2020-07) KAVYASHREE, T.L; Dr. M.L. SATYANARAYANA
    The present study was conducted in diabetes induced rats with special emphasis on efficacy of combined herbal extracts. Gymnema sylvestre and Momordica charantia were used at the dose of 200 mg/kg b.w each (100per cent) and Gymnema sylvestre + Momordica charantia at the dose rate of 100 mg/kg b.w each (50per cent) and Glibenclamide at the dose rate of 300 µg/kg b.w (50per cent) were administered in combination and compared with an oral hypoglycaemic drug, Glibenclamide, for a period of 45 days. There was a significant difference in various parameters like body weight, serum glucose, serum cholesterol, serum triglycerides, ALT, AST, haemoglobin, RBC count, WBC count, platelets count and antioxidant enzymes (SOD, GPx and CAT) in diabetic rats as compared to normal control rats. The partial alleviation of diabetic effects was observed in all combination of treatments in the present study