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Subject: Veterinary Surgery and Radiology × Author: Kaushal, Sara × Start date: 2020 × Type: Thesis ×
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    ThesisItemOpen Access
    Studies on the diagnosis and management of corneal ulcer in dogs
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2021-05) Kaushal, Sara; Jadon, N.S.
    Twenty four dogs of either sex for the treatment of corneal ulcers were used in this study. The animals were randomly divided into three groups having equal number of animals viz. group I treated with medicinal therapy, group II treated with membranoplasty and medicinal therapy and group III, treated by application of contact lens along with tarsorrhaphy and medicinal therapy. The diagnosis was made on the basis of detailed ophthalmic examination and various diagnostic tests such as vision reflex tests, Schirmer’s tear test, fluorescein dye test, microbiological sampling, ophthalmoscopic examination and tonometry on the day of presentation and on the day of suture removal. Besides this, various clinical, haematological (Hb, TEC, PCV, TLC and DLC) and biochemical (serum glucose, total protein, serum albumin and serum globulin) parameters were studied at 0, 1st, 2nd, 3rd, and 4th week using standard protocols. On the basis of parameters observed in this study, it was concluded that the clinical parameters did not reveal any significant change between the different treatment groups and were fluctuating within the normal physiological limits. Macroscopically, conjunctival infection and chemosis, corneal edema, transparency, decreased tear production, fluorescein dye uptake, pupillary and blink reflexes and neovascularisation were observed on the corneal wounds of different groups. The results suggested that early corneal healing with maximum reduction in conjunctival infection, edema, neovascularization was observed in the animals of group III, followed by groups II and I. It was concluded that medicinal treatment, which included eye ointment (neosporin: neomycin, bacitracin and polymyxin B), anti-inflammatory agent (carprofen), systemic broad-spectrum antibiotic (doxycycline) and carboxymethyl cellulose eye drops (refresh tears) was found to be effective in uncomplicated, superficial ulcers. However, many complications such as epiphora, keratitis, corneal scarring and edema were observed. Membranoplasty/third eyelid flap technique with medicinal treatment in animals of group II, resulted in effective healing of the corneal ulcer as compared to the animals of group I. Complications including flap dehiscence, edema and scarring were observed. Application of contact lens along with tarsorrhaphy and medicinal treatment in group III was found to be most efficacious for the management of corneal ulcers, as minimal postoperative complications were observed in this group, along with faster recovery and earlier restoration of vision as compared to the other two treatment groups.