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ThesisItem Open Access Assessment of phytochemicals, antioxidant and anti-inflammatory potential in sixteen plant species of Asteraceae(G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2021-01) Rawat, Deepti; Rao, P.B.Sixteen different plant species of family Asteraceae were selected for evaluation of their phytochemical profile in two different solvents. The extraction yield (%) was maximum in Ageratum houstonianum (56.94±0.13 and 66.14±0.20) in both aqua acetone and aqua methanol, respectively. Among the plant species extracts, comparatively higher DPPH activity (%) was obtained in Lagascea mollis (78.93 and 86.84, respectively in aqua acetone and aqua methanol); FRAP (μg TE/mg) in Ageratum houstonianum (166.18±0.13) and Vernonia cinerea (177.86±2.40); and TAA (μg VCE/mg) values in Emilia sonchifolia (90.28±1.36) and Erigeron bonariensis (164.33±0.57) in aqua acetone and aqua methanol, respectively. The values of TPC (μg GAE/mg) were higher in Galinsoga parviflora (67.67±0.37) and Erigeron bonariensis (87.09±0.48); and TFC in Ixeris polycephala (19.76±0.08 and 11.70±0.7 in aqua acetone and aqua methanol, respectively). SOD (DU/mg FW), POD (nmole/mg protein), and CAT (μmole/mg protein) activity were higher in Erigeron bonariensis (20.01±0.02), Cirsium arvense (109.35±0.69), and Xanthium strumarium (45.52±0.13), respectively. The Anti-inflammatory activity (%) was higher in Gnephalium pensylvanicum (89.67±0.45) and Ageratum houstonianum (98.38±0.34) in aqua acetone and aqua methanol extracts, respectively. The anti-bacterial activity (%) was maximum in Blumea sinuata (75.00), followed by in Y. japonica (68.75). Out of total compounds identified by GC-MS analysis in six plant species, the major important bioactive compounds are: guanosine (neuroprotective potential), arbutin (astringent and disinfectant properties), n-hexadecanoic acid (hemolytic, pesticide, lubricant activities), and lupeol (anticancer and anti-inflammatory activities) in Blumea sinuata; beta.-amyrin (anti-fungal and anti-inflammatory activity), betulin (Anti-HIV activity) in C. arvense; and Phytol (hypocholesterolemic, antimicrobial, anticancer, and anti-inflammatory) in all the species. Thus, among 16 different plant species, Lagascea mollis, Erigeron bonariensis, Ageratum houstonianum, Blumea sinuata, Cirsium arvense and Ixeris polycephala are more promising for scientific foundation to exploit potential natural plant resources in terms of antioxidants, anti-inflammatory and anti-bacterial.ThesisItem Open Access Isolation and characterization of microalgae and their biomass production(G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2016-06) Rawat, Deepti; Sharma, A.K.
