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Book Chapters (English)

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Now showing 1 - 9 of 28
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    Book chapterItemOpen Access
    IPR ISSUES IN Bl0lNFORMATlCS
    (TANUVAS, Chennai, 2009-09) Dhanapalan, P.; TANUVAS
    IPR is an acronym that hardly needs to be expanded nowadays. We encounter intellectual property at every step of our life today. The design on the bed sheet and the pillow covers, the bed and other items of furniture in the house, the cereals for break fast, the pasteurised milk in tetra pack, the soft drinks and their bottles, the television, the personal computer, the gas stove, the microwave oven, the refrigerator, the vehicles, the weighing machine, the books, the films, the music cassettes, the tiles, the paints, and practically everything we use is the product of man’s ingenuity, knowledge and skill, besides labour and capital; and it falls under some kind of intellectual property that had to be respected before the item could be lawfully manufactured.
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    Book chapterItemOpen Access
    GEOGRAPHIC INFORMATION SYSTEM AND ITS APPLICATIONS IN ANIMAL SCIENCES
    (TANUVAS, Chennai, 2009-09) Kathiravan, G.; TANUVAS
    A Geographical information System (GIS) can be used as a tool for any discipline which handles with data that can be connected with geographical locations, such as countries, regions, communities or geo- coordinates. GIS is about to become tools for everyone. The need for using this system also in the field of veterinary medicine has been emerging during the last decade (Babalobi et al., 2002).
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    Book chapterItemOpen Access
    IT APPLICATIONS AND BIOINFORMATICS IN MOLECULAR DIAGNOSIS
    (TANUVAS, Chennai, 2009-09) Vijayarani, K.; TANUVAS
    The evolution of molecular biology from its birth as a distinct field of science in the 1960s through the present has seen a major shift in emphasis from the creation of novel data- generating methods to the creation of novel informatic systems for the analysis of high dimensional datasets. Functional genomics and proteomics involve the simultaneous analysis of hundreds or thousands or expressed genes or proteins and have spawned the modern discipline of computational biology.
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    Book chapterItemOpen Access
    APPLICATION OF BIOINFORMATICS IN GENE CLONING AND EXPRESSION
    (TANUVAS, Chennai, 2009-09) Manoharan, S.; TANUVAS
    During 1970’s genetic research was thrown back into gear by what at the time was described as a revolution in experimental biology. A whole new methodology was developed, enabling previously impossible experiments to be planned and carried out, if not with ease, then at least with success. These methods, referred to as recombinant DNA technology or genetic engineering, and having at their core, the process of gene cloning, sparked another great age of genetics.
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    Book chapterItemOpen Access
    BlOlNFORMATlCS IN CARDIOVASCULAR MEDIClNE
    (TANUVAS, Chennai, 2009-09) Selvaraj, P.; TANUVAS
    Cadiovascular disorders, Metabolic and endocrine disorders remain major epidemic disorders and is the leading cause of mortality and morbidity in both developed and developing economies. In lndia, the mortality and morbidity due to these disorders remain very high. Despite steady progress, atherosclerotic cardiovascular disease remains a growing public health burden and advances in cardiovascular research will not realize their full impact unless translated to care of individual patients.
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    Book chapterItemOpen Access
    BIOINFORMATICS IN FOOD ANIMAL MEDICINE
    (TANUVAS, Chennai, 2009-09) Srinivasan, S.R.; TANUVAS
    Bioinformatics is a composite field that applied the knowledge from applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry and biochemistry to solve biological problems. This is the field where millions of research hours and the maximum investment are being done in developed countries to explore better and also to obtain effective results based on data. The simplest task to start with in the field of bioinformatics is to create and maintain databases of biological information.
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    Book chapterItemOpen Access
    COMPUTATIONAL VACCINOLOGY
    (TANUVAS, Chennai, 2009-09) Prabhakar, T.G.; TANUVAS
    Vaccination is the preventive method of choice to fight against microbial pathogens and presents the best cost/benefit ratio among current clinical and pharmaceutical practices. There are many reasons and serious threats which make the development of new advanced vaccines necessary, for example, avian flu the spread of antibiotic-resistant strains of pathogens. Newer approaches to vaccine development are now urgently needed for two reasons.
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    Book chapterItemOpen Access
    MICROARRAY IN BIOINFORMATICS
    (TANUVAS, Chennai, 2009-09) Raj, G. Dhinakar; TANUVAS
    Genes are differentially expressed in - Different cell types (e.g. muscle cells, fibbroblasts) - Environmental conditions (e.g. heat shock, nutrient deprivation) - Developmental phases (e.g. embryonic day 10) - Cell-cycle stages (e.g. G1 phase) - Disease states (e.g. tumor cells, virus-infected cells) Gene expression is primarily regulated at the level of transcription. Hence, the number of mRNA copies in a cell for a particular gene is a good indicator of that gene’s expression (number of proteins).
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    Book chapterItemOpen Access
    DATA MINING FOR DRUG DISCOVERY
    (TANUVAS, Chennai, 2009-09) Dhanapalan, P.; Sujatha, P.L.; Devendran, P.; TANUVAS
    Data mining sifts through huge amounts of information and extracts previously unrealised information about molecular compounds, product portfolio, clinical studies, and customer information that can be applied to accelerate drug discovery and development. For example, you could match desirable biochemical specifications with disease. and patient characteristics, and select compounds with the highest probability of a favourable safety and efficacy profile.