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ThesisItem Open Access CLINICO - BIOCHEMICAL STUDIES ON UTERINE TORSION IN GRADED MURRAH BUFFALOES WITH SPECIAL REFERENCE TO ITS PROGNOSIS(SRI VENKATESWARA VETERINARY UNIVERSITY, TIRUPATI - 517 502, A.P, 2016-05) SRINIVASA RAO NAIK, B; SRINIVAS, MABSTRACT : The incidence of uterine torsion in the present study was 63.30 per cent out of all the difficult parturitions from July 2014 to October 2015 (two calving seasons). Uterine torsion was recorded in 8 primiparous (11.59%) and 61 pluriparous (88.41%) buffaloes at term, 2-3 days after onset of parturition and 9 months of gestation in 53 (76.81%), 10 (14.49%) and 6 (8.70%) buffaloes, respectively. Post cervical torsion was at 97.10 per cent followed by pre cervical uterine torsion which was 2.90 per cent. Right sided torsion was more common (91.30%) when compared with the left sided uterine torsion (8.70%). The incidence of severe degree (>270->360°) of uterine torsion was 55.07 per followed by 27.54 per cent with moderate (>180-270o) and 17.39 per cent with mild (90-180o) degrees of torsion. The condition was observed since 12-24 hours in 44.93, >24-36 hours in 40.58 and >36 hours in 14.49 per cent of the buffaloes before they were presented for treatment. Most of the fetuses were in anterior longitudinal presentation (96.83%) while only a few (3.17%) were in posterior longitudinal presentation. Male and female calves were born at 57.14 and 42.86 per cent, respectively among them, 31.75 and 68.25 per cent were live and dead, respectively. The success rate of detorsion by modified Schaffer’s method based on the degree of torsion was 100.00, 94.73 and 86.84 per cent in 90-180°, >180-270° and >270->360°, respectively while it was 100.00, 92.86 and 60.00 per cent in buffaloes presented at 12-24 hours, >24-36 hours and >36 hours, respectively. Uterine rupture was evident in 2 out of 5 buffaloes and 2 out of the 4 buffaloes which were presented with >270°->360° uterine torsion, and >36 hours after onset of uterine torsion, respectively. With the advancement of the degree and duration of uterine torsion, the haematological changes showed lymphocytopenia, neutrophilia with shift to left, esionophila and monocytosis. Blood glucose levels significantly increased with increased duration and degree of uterine torsion. Calcium were significantly higher and showed a transient decrease with increase in degree and duration of torsion while, serum phosphorus levels showed a non-significant decrease with degree and duration. Serum creatinine and AST levels in the present study showed a significant increase with increase in degree and duration of uterine torsion. From the present study it was concluded the level of calcium, creatinine and AST could be used as an indicator for duration and prognosis of detorsion in buffaloes. Thus, the attention of the veterinarian must be directed either to advise rolling of the case as soon as possible or to salvage the animal in delayed cases presented > 36 hours to prevent financial losses to the farmer.