Thumbnail Image

Thesis

Browse

20081
Reset filters
Author: ANIL KUMAR, B × End date: 2008 × Start date: 2008 × Thesis Type: M.V.Sc. ×
Reset filters

Search Results

Now showing 1 - 1 of 1
  • Thumbnail Image
    ThesisItemOpen Access
    STUDIES ON THE TOXICITY OF BT COTTON PLANTS INCORPORATED IN THE FEED OF SHEEP
    (SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2008-11) ANIL KUMAR, B; GOPALA REDDY, A(MAJOR); USHA RANI, M; ANJANEYULU, Y
    ABSTRACT: A total 32 Sheep of one-year age belonging to Deccani breed were randomly divided into four groups consisting of eight sheep in each group. Group 1 was maintained on basal diet and 2 on non-Bt and Green fodder @ 1.5Kg each/Sheep, 3 on 50% Bt cotton+50% green fodder and 4 was maintained on Bt cotton plant material ad libitum and concentrate feed @300g/sheep/ day. All the groups of sheep were maintained for 90 days The introduction by recombinant DNA technology of new gene into cotton crop by animals has raised important questions about the safety of novel feeds. Studies have been therefore conducted to assess the safety of novel protein in the feed of sheep The performance parameters were recorded at monthly intervals, biomarkers of hepatic damage, renal damage, lipid profile, protein profile, levels of Cry1Ac toxins in serum and haematolgical profile were also assessed. Screening for pesticide residues, concentration of gossypol and levels of heavy metals in cotton plants were estimated at the middle age of crop. Histopathological studies and estimation of TBARS, GSH, SOD and Catalase were done at the end of 90 days (3 months). Following 90 days of feeding, no adverse effects or mortality were observed during the conduct of experimental observation.There was no significant change in the growth parameters, serobiochemical profile, anti-oxidant defense profile and haematological parameters in Bt cotton plant material fed groups as compared to basal diet control and non-bt cotton fed group. In conclusion, the study demonstrated that feeding of sheep with Bt cotton plant material at different growth stages of plant did not produce any untoward effects on health.