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ThesisItem Open Access EVALUATION OF GERIATRIC DOGS FOR CERTAIN DISEASES WITH SPECIAL REFERENCE TO CONGESTIVE HEART FAILURE(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2014-06) AMAR, G.S; NALINI KUMARI, K(MAJOR); VAIKUNTA RAO, V; SHOBHA MANI, B; SURESH KUMAR, R.VABSTRACT : The aim of the investigation was to study the prevalence of pattern of certain diseases in geriatric dogs, to study the clinicopathological and biochemical changes in the diseases detected and to undertake therapy in congestive heart failure. The study revealed the prevalence of hepatic disease, renal disease and congestive heart failure in geriatric dogs as 8.33 per cent, 7.29 per cent, and 6.25 per cent respectively. The most prominent clinical signs observed were hypersalivation, irritability, vomition, decreased appetite, exercise intolerance and ascites in geriatric dogs with hepatic disease. The clinical signs observed in geriatric dogs with renal disease were hypersalivation, vomition, irritability and decreased appetite. Clinical examination of geriatric dogs with congestive heart failure revealed dyspnea, exercise intolerance, ascites, nocturnal cough and decreased appetite. Haematological values showed the results of normal haemogram and leucogram in geriatric dogs with hepatic disease, renal disease and congestive heart failure. In serum biochemistry profile elevated blood urea nitrogen, creatinine, triglycerides, cholesterol, fibrinogen, CK-MB, ALT, and decreased total protein and albumin were observed in geriatric dogs with hepatic disease, renal disease and congestive heart failure. Qualitative assessment of cardiac troponins in geriatric dogs with congestive heart failure was found to be positive. No significant changes were noticed in the urinalysis of geriatric dogs with congestive heart failure. Where as low specific gravity, proteinuria and alkaline urine was observed in geriatric dogs with renal disease. The reduction in specific gravity, pH, and presence of urobilinogen and protein in urine was observed in geriatric dogs suffering with hepatic disease. No significant difference in values of blood pressure in geriatric dogs suffering with hepatic and renal disease. Whereas significant elevation was noticed in both systolic and diastolic pressure values in geriatric dogs with congestive heart failure. Thoracic radiography revealed cardiomegaly and pulmonary edema. In electrocardiography left ventricular enlargement, atrial fibrillation and left atrial enlargement were common in geriatric dogs with congestive heart failure. The M-mode echocardiography in congestive heart failure of geriatric dogs showed elevated left ventricular internal dimensions, decreased left ventricular posterior wall thickness and decreased left ventricular contractility indices. Combination of pimobendan, enalapril, furosemide and L-carnitine was found to be effective in the therapeutic management of congestive heart failure associated with dilated cardiomyopathy in geriatric dogs.