Thumbnail Image

Thesis

Browse

20171
Reset filters
Subject: Veterinary Surgery and Radiology × Author: CHANDRA SEKHAR, K × End date: 2017 × Start date: 2017 ×
Reset filters

Search Results

Now showing 1 - 1 of 1
  • Thumbnail Image
    ThesisItemOpen Access
    COMPARATIVE EVALUATION OF ROPIVACAINE, ROPIVACAINE – DEXMEDETOMIDINE AND ROPIVACAINE – CLONIDINE COMBINATIONS FOR EPIDURAL ANALGESIA IN CATTLE
    (SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2017-12) CHANDRA SEKHAR, K; VEENA, P(MAJOR); SURESH KUMAR, R.V; JAGAPATHI RAMAYYA, P
    ABSTRACT: Eighteen cattle of either sex presented to the clinic with different surgical conditions like urolithiasis, tumors in perineal region and tail injuries were utilized to study the effects of ropivacaine, ropivacaine – dexmedetomidine and ropivacaine – clonidine combinations for epidural analgesia. The animals were divided into three groups of six animals each. Group I received ropivacaine (0.75%) @ 0.25 mg/kg b.wt at sacrococcygeal space. Group II animals received ropivacaine (0.75%) @ 0.25 mg/kg b.wt and dexmedetomidine @ 5 μg/kg b.wt in the sacrococcygeal space. Group III animals received ropivacaine (0.75%) @ 0.25 mg/kg b.wt and clonidine @ 2 μg/kg b.wt at sacrococcygeal space. The fastest onset of analgesia was produced by ropivacaine –dexmedetomidine combination followed by ropivacaine – clonidine. Profound analgesia was observed in animals following ropivacaine – dexmedetomidine epidural injection. Animals in group II showed rapid abolition and prolonged reappearance of all reflexes followed by group III and group I animals. Rectal temperature showed non significant decrease in all groups during post epidural analgesia. A non significant increase in respiratory rate was observed in cattle following ropivacaine and ropivacaine – clonidine epidural analgesia. Whereas, a non significant fall was noticed in respiratory rate during ropivacaine – dexmedetomidine combination. A non significant increase in heart rate was recorded after epidural administration of ropivacaine in group I animals. Group II and III animals showed a non significant decrease in heart rate throughout the period of study. ECG studies did not reveal any abnormalities except sinus arrhythmia in all animals. In group I and III, non significant increase in Hb and PCV values were observed in the present study. Non significant decrease in Hb and PCV values were recorded in animals subjected to ropivacaine – dexmedetomidine analgesia. A non significant increase in AST, ALT levels was noticed in all groups of animals. The study suggests that dexmedetomidine is a better adjuvant than clonidine in producing epidural analgesia as far as cardio – respiratory and haemato – biochemical parameters are concerned. Therefore, ropivacaine – dexmedetomidine combination can be recommended for safe epidural analgesia in cattle