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20161
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Subject: Veterinary Surgery × End date: 2016 × Start date: 2016 ×
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    ThesisItemOpen Access
    STUDY ON ANAESTHETIC SPARING EFFECT OF BUTORPHANOL ACEPROMAZINE ATROPINE (BAA) AND TRAMADOL ACEPROMAZINE ATROPINE (TAA) PREMEDICATION ON INDUCTION AND MAINTENANCE ANAESTHESTIC PROTOCOLS FOR ORTHOPAEDIC SURGERIES IN DOGS.
    (SRI VENKATESWARA VETERINARY UNIVERSITY, TIRUPATI – 517 502, A.P, 2016-02) NITIN, C.J; HARI KRISHNA, N.V.V ( Major ); RAGHUNATH, M; VENKATA NAIDU, G
    ABSTRACT : The present study was conducted to assess the anaesthetic sparing effect of butorphanolacepromazine- atropine and tramadol-acepromazine-atropine pre-medication on induction and maintenanceanaesthetic protocols in dogs operated for orthopaedic surgeries. The study was conducted on 18 dogspresented to the Department of Veterinary Surgery & Radiology, NTR College of Veterinary Science,Gannavaram for different orthopaedic surgeries. The animals were randomly divided into three groups of six animals of either sex in each group (n=6). Group-I received butorphanol, acepromazine and atropine @ 0.1, 0.03 and 0.02 mg/kg b.wt. and group-II received tramadol, acepromazine and atropine @ 4, 0.03 and 0.02 mg/kg b. wt. and group-III received acepromazine and atropine @ 0.03 and 0.02 mg/kg b.wt., respectively given IM 30 min. prior to induction with ketamine-diazepam administered IV ‘to effect’ and maintained with isoflurane in oxygen. The changes in body temperature, cardiovascular, pulmonary, haeamatobiochemical parameters were studied. Butorphanol group had good sedation and the quality of induction compared to tramadol group. The mean dose of ketamine and diazepam used for induction was significantly low in the butorphanol and tramadol group compared to the control group. The mean vaporizer setting for maintenance, total quantity of isoflurane consumed were significantly low in butorphanol group and tramadol compared to control group. Among butorphanol and tramadol groups, butorphanol had significantly lower values. Hb, PCV, TEC and TLC showed non-significant changes in all the three groups. The cardiovascular and respiratory parameters showed significant reduction following pre-medication in all the three groups and increased following induction and maintenance of anaesthesia. The time of extubation was significantly low in butorphanol group compared to other two groups. In all the animals recovery was smooth. The serum cortisol level showed a significant decrease after pre-medication and during surgical anaesthesia in the butorphanol and tramadol group indicating lower stress response to surgery. Butorphanol group showed better sparing effect than tramadol group in dogs induced with ketamine-diazepam followed by isoflurane maintenance in canine orthopaedic surgeries.