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  • ThesisItemOpen Access
    STUDIES ON INFLUENCE OF PHENOTHIAZINE AND BENZODIAZEPINE TRANQUILIZERS ON PROPOFOL ANAESTHESIA IN DOGS
    (Sri Venkateswara Veterinary University, TIRUPATI – 517 502,A.P, 2003-09) MALLIKARJUNA RAO, Ch; HARA GOPAL, V (Major); SURESH KUMAR, R.V; SRILATHA, Ch
    ABSTRACT : Twelve dogs were utilized to study the effects of propofol on induction and maintenance after premedication with triflupromazine hydrochloride and diazepam. The animals were divided into two groups of six animals in each group. Triflupromazine hydrochloride@ 1 mg/ kg body weight and diazepam @ 0.5 mg/kg body weight were given intravenously in group I and group II respectively. Propofol was given intravenously @ 5mg/kg body weight after premedication and maintained by continuous infusion of propofol @ 0.4 mg/kg/minute in 5 per cent dextrose normal saline in both the groups. Induction was smooth and excellent in both the groups. Diazepam premedicated animals showed good muscle relaxation and abolition of all reflexes were noticed early than group I. The recovery from anaesthesia was smooth without any postanaesthetic complications in both the groups. Rectal temperature and respiratory rate did not show any significant changes between two groups. Heart rate did not show any significant fall in group I and significant fall up to 15 minutes in group II followed by gradual increase to near normally in remaining period. Sp02 values were within normal range during the entire period of observation. Electrocardiographic findings revealed no arrhythmias and conduction abnormalities in both the groups. The various haematological parameters like packed cell volume (PCV), haemoglobin(Hb) values did not show any significant decrease. Significant difference between two groups in packed cell volume (PCV) and haemoglobin(Hb) were noticed. Erythrocyte sedimentation rate (ESR) did not show any significant changes in both the groups. Changes in the Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) values were not significant and within normal range in both the groups.
  • ThesisItemOpen Access
    HALOPERIDOL AS AN ADJUNCT TO BARBITURATE AND NON-BARBITURATE ANAESTHESIA IN DOGS
    (Sri Venkateswara Veterinary University, TIRUPATI – 517 502,A.P, 2003-09) PRAKASH KUMAR, B; R.V.SURESH KUMAR, R.V (Major); HARA GOPAL, V; SRILATHA, Ch
    ABSTRACT : Twelve healthy female dogs brought for animal birth control programme were divided into two groups of six animals each to study the effects of haloperidol as an adjunct to thiopentone sodium and ketamine hydrochloride. Haloperidol was given intravenously @ 0.87 mg/kg body weight in both the groups. All the dogs assumed sternal recumbency following haloperidol administration but were responding to painful stimuli. This was followed by administration of thiopentone sodium @ 20 mg/kg body weight and ketamine hydrochloride @ 10 mg/kg body weight in group I and group II respectively. The induction was smooth and rapid in group I but was delayed in group II. The mean duration of anaesthesia was 41.0 ± 0.94 minutes in group I where as it was 28.0 ± 4.09 minutes in group II which required incremental dose of ketamine approximately at 30 minutes of observation period. The recovery was smooth in group I, but associated with micturition, shivering and moderate vocalization in group II. Respiratory or heart rates showed significant decrease while temperature showed non-significant decrease in both the groups. PCV, Hb, ESR and TLC values decreased non-significantly in both the groups. BUN and creatinine levels showed transient non significant increase in group I and II. SpO2 values remained within the physiological limits in both the groups. ECG studies did not reveal any significant changes in PQ, PR, QRS complexes except primary T wave changes in two animals. The study suggests that the combination of haloperidol with thiopentone and ketamine were compatible and safe and are recommended for clinical use in dogs.
  • ThesisItemOpen Access
    COMPREHENSIVE STUDY ON VARIOUS DENTAL PROBLEMS IN CANINES
    (Sri Venkateswara Veterinary University, TIRUPATI – 517 502,A.P, 2003) VANI, G; HARA GOPAL, V
    ABSTRACT : The present investigation deals with comprehensive study on various dental problems in canines. Out of three hundred and fifty five animals that were screened one hundred and seventy three dogs (48.73%) showed various dental problems. These dental problems were divided into four major categories, such as developmental abnormalities, irregular wear and tear, diseases in tooth substance and diseases of alveoli and gums. Out of the total dental problems 6 (3.46%) had developmental abnormalities, 28 (16.18%) had irregular wear and tear, 92 (53.17%) showed diseases of tooth substance and 47 (27.16%) showed diseases of alveoli and gums. Among a total of 173 canines that had different dental problems males constiuted 92 (53.17%) and females 81 (46.82%). 10 alsatian (5.78%), 5 daschund (2.89%), 7 dobermann (4.404%), 53 pomeranian (30.63%) and 98 mongels (56.64%) showed various dental problems. Mongrels showed highest incidence followed by pomeranians.Incidence was more in 4-8 yrs age group animals (6.3%). Dogs fed on soft diet showed symptoms like dental calculus and caries and dogs fed an hard diet showed gingivitis. Halitosis was the most commonly observed symptom in 50% of the cases, followed by excessive salivation, receding of gums, periodontitis and bleeding from gums. The various types of organisms isolated in 25 random samples of periodontitis were Escherishia coli (88%) Streptococcus (84%), Proteus (84%) Salmonella (64%) Staphylococcus (44%), Bacteroides (28%) and Pseudomonas (20%). ABST results showed that majority of cases were sensitive to Amikacin (62%) followed by Ciprofloxacin (51%). Diagnosis of alveolar periostitis and periodontitis required radiological intervention. Three oral tumors were diagnosed as odontoma, oral papilloma and Basal cell carcinoma on histopathological examination. Appropriate therapeutic methods like scaling,extraction of tooth and excision of tumor etc., were adopted in different dental problems.
  • ThesisItemOpen Access
    EVALUATION OF CERTAIN ANAESTHETIC COMBINATIONS IN DOGS
    (Sri Venkateswara Veterinary University, TIRUPATI – 517 502,A.P, 2003-09) SURESH BABU, K; HARA GOPAL, V; SURESH KUMAR, R.V; SREELATHA, Ch
    ABSTRACT : Twenty four dogs of either sex were divided into 4 groups to study the changes in clinical, physiological, haematological, biochemical, pulse oximetry and ECG during barbiturate anaesthesia under premedication. The premedicants used were triflupromazine hydrochloride, diazepam, ketamine and Xylazine. The induction was smooth and rapid after any premedication except with diazepam. Incremental doses of thiopentone were required irrespective of the premedicant used to maintain/ prolong surgical plane of anaesthesia. Incremental pentothal prolonged the recovery period in all the groups. Lack of appreciable changes in physiological and other parameters indicate the choice of premedicant to barbiturate anaesthesia is by preference.
  • ThesisItemOpen Access
    STUDIES ON CHEMICAL CASTRATION IN DOGS
    (SRI VENKATESWARA VETERINARY UNIVERSITY , TIRUPATI – 517 502 (A.P) INDIA, 2003-08) VENU GOPALA RAO, Y; SURESH KUMAR, R.V (Major); HARA GOPAL, V; CHANDRASEKHARA RAO, T.S
    ABSTRACT : The present study was undertaken to evaluate and compare the efficacy of chlorhexidine digluconate and potassium permanganate for performing chemical sterilization in dogs. Twenty four non-descript stray dogs were divided into two groups of twelve animals each. Six animals were utilized to study the effects upto fifteen days and the remaining six were utilized to study the effects upto thirty days. Under general anaesthesia the chemical agents were administered intratesticularly by strictly following aseptic and painless procedures. The clinical symptoms, macroscopic, ultrasono-graphic, contrast radiographic and histopathological changes were recorded and compared. The rectal temperature, pulse and respiratory rates were not altered significantly in both the groups during the period of study. The Scrotal circumference increased significantly in both groups but it was more in group II. Clinically there was a change in gait and micturition behaviour in both the groups. None of the animals showed licking or biting behaviour. Gross changes at 15th day showed severe and moderate adhesions between testes and other structures in group I and group II respectively. The size of testes was reduced and severe adhesions were found on 30th day in group I and II . Testicular hyperechogenicity was a prominent feature in group I animals at 15th and 30th post injection days. Group II animals showed hypo or anechoic testicular parenchyma on 15th day which became hyperechoic on 30th day. Contrast radiography studies revealed tortuous vas deferens on 15th day in both groups. At 30th day obliteration of tubular lumen with shrinkage was noticed. Microscopic studies revealed calcification in seminiferous tubules in group I on 15th day. Edema and desquamation of tubular epithelium were found in group II. On 30th day sections showed peritubular fibrosis in group I and atrophy of seminiferous tubules in group II.
  • ThesisItemOpen Access
    STUDIES ON DIAGNOSIS OF LOWER RESPIRATORY TRACT AFFECTIONS/DISORDERS WITH SPECIAL REFERENCE TO TRACHEOBRONCHOSCOPY IN DOGS
    (SRI VENKATESWARA VETERINARY UNIVERSITY , TIRUPATI – 517 502 (A.P) INDIA, 2007-12) VINEESH, N (Major); SURESH KUMAR, R.V (Major); SREENU, MAKKENA; VAIKUNTA RAO, V
    ABSTRACT : The present investigation was carried out on diagnosis of respiratory tract affections/disorders with special reference to tracheobronchoscopy in dogs. Out of 623 animals that were screened, 116 dogs (33.86%) showed various respiratory problems. Among the dogs with respiratory tract disease incidence of lower respiratory tract was 54.98 per cent and upper respiratory tract was 45.02 per cent. Out of these, dogs with lower respiratory tract diseases 21 (18.10%) had tracheitis, 12 (10.34%) had haemorrhagic tracheitis, 3 (2.59%) showed tracheal collapse, 4 (3.44%) had foreign bodies in trachea, 46 (39.66%) suffered with tracheobronchitis 21 (18.10%) had bronchopneumonia and 9 (7.76%) showed metastatic lower respiratory tract lesion. No significant changes were observed in electrocardiographic studies. Based on clinical presentation cases were divided into two groups. Among them radiography as well as tracheobronchoscopic procedures conducted to diagnose different incidences. Radiography was useful in diagnosing bronchopneumonia, metastatic lesions in lungs and tracheal collapse. Tracheobronchoscopic examination revealed conditions like tracheitis, tracheobronchitis, bronchopneumonia, haemorrhagic tracheitis, foreign body in trachea and tracheal collapse. Haematological parameters viz., group II dogs showed marked neutrophilia, eosinophilia lymphocytopaenia and leucocytosis whereas no significant changes were observed in total erythrocyte counts and packed cell volume values. C-reactive protein levels significantly marked increase in the values in case of group II (affected) whereas glucose and total protein values were within normal limits. Antibiotic sensitivity test showed that, enrofloxacin as sensitive antibiotic followed by gentamicin and chloramphenicol to the samples collected randomly from affected cases. The cases were effectively treated using the antibiotic based on ABST results in addition to corticosteroids, antihistaminic, antipyretics and supportive therapy.